Meet the editor

Dr. Turner received his medical degree from the Medical College of Wisconsin and completed a neurology residency at Stony Brook University, the State University of New York. He subsequently completed a neuro-oncology fellowship at Duke University, North Carolina. He has been practicing neuro-oncology for over ten years and has served as the director of the neuro-oncology programs at Geisinger Medical Center in Pennsylvania

and at Saint Luke's Hospital in Kansas City. He has worked to develop a multidisciplinary treatment paradigm, which integrates clinical trials with chemo and radiation therapy, intrathecal chemotherapy, and stereotactic radiosurgery. He created a comprehensive care plan that includes physical and occupational therapy, nutritional planning, psychiatric and neuropsychologic evaluation, and palliative care. He is currently a neuro-oncologist at the University of California, Irvine.

Contents

**Section 1**

**Section 2**

*and Anil Nanda*

**Section 3**

in Pediatric Patients

of CNS Malignancies *by Scott George Turner*

**Preface XI**

Introduction **1**

**Chapter 1 3**

Pediatric Brain Tumors **7**

**Chapter 2 9**

**Chapter 3 37**

Surgical Management of CNS Tumors **49**

**Chapter 4 51**

**Chapter 5 65**

Introductory Chapter: The Current State of the Treatment

Pediatric Brain Tumors: From Modern Classification System

*by Ahmad Ozair, Erum Khan, Vivek Bhat, Arjumand Faruqi* 

*by Raghunadharao Digumarti and Venkata Pradeepbabu Koyyala*

*Ericka León-Alvárez, Natael Olvera González, Alfonso Marhx-Bracho, Javier Terrazo-Lluch, José Luis Pérez-Gómez, Jorge Alberto Ocon Rodríguez,* 

Awake Craniotomy and Brain Mapping for Brain Tumor Resection

*by Roberto Garcia-Navarrete, Javier Terrazo-Lluch, Alfonso Marhx-Bracho, Ericka León Alvárez, Natael Olvera González, Beatriz Alvárez-Mora, Rosario Aguilar Silva, Cointa Arroyo, Vianey Maceda Morales,* 

*Luz María Cordero, Daniel Magos Rodríguez, Sandra Luz Lizarraga-Lopez,* 

Multimodal Neuronavigation for Brain Tumor Surgery *by Roberto Garcia-Navarrete, Constantino Contreras-Vázquez,* 

*Judy Castañeda Goyes and Juan Alberto Díaz Ponce Medrano*

*Ana Niembro Zúñiga and Juan Alberto Díaz Ponce Medrano*

to Current Principles of Management

Patterns of Care of Childhood Cancers in India

## Contents



Preface

The book *Central Nervous System Tumors* represents the contribution of many experts in the field, each with his own specialty and interests. The management of patients with tumors of the central nervous system (CNS) is complex and involves the expertise of many disciplines including neuro-oncology, neuroradiology, neurosurgery, radiation oncology, neuropathology, and more. Many of our patients are quite debilitated and require the aid of physical and occupational therapy, spiritual counseling, pain management, and palliative care. Our field has changed greatly over the past several years as we gain a better understanding of the mechanisms of tumorigenesis and the genes involved. Many of them can be targeted with new pharmaceuticals, and immunotherapy is a very active area of research. We rely heavily on new breakthroughs from basic science research labs around the world.

I am grateful for the wonderful and exciting contributions from the many authors that have helped with the publication of this book, and I remain hopeful for the future of the field with the many new advances that are sure to come in the years ahead. I also would like to thank our *IntechOpen* colleagues for their help and

**Dr. Scott George Turner**

University of California, Irvine, Orange, CA

Associate Professor of Neurology, Department of Neuro-Oncology,

support in bringing the most up-to-date findings to its readers.
