**2. Prevalence and pathogenies of NAFLD**

NAFLD, the primary cause of chronic liver disease seen in developed countries, is presently highly prevalent among the Asian population. According to recent estimates, the global prevalence of NAFLD is reported at 25 percent and the combined prevalence rate is 27.4 percent in Asia [7]. Two hypotheses are framed for the pathogenesis of NAFLD. The first hit is a two-hit theory where fat accumulation in the liver is caused due to diet, obesity and insulin resistance and the first hit further exposes the liver to more insults called second hit which activate inflammatory pathways and fibrogenesis [8]. In continuation, a multi-hit hypothesis was suggested where numerous factors like environment, dietary habits and genetic led to the development of liver damage [9].
