Role of Anti-Viral Drugs in Combating SARS-CoV-2

*Sweta Kamboj, Rohit Kamboj, Shikha Kamboj, Rohit Dutt, Reeva Chabbra and Priyanka Kriplani*

## **Abstract**

Viruses are the eventual assertion of parasitism, they not only take nutriments from the host cell, apart from that they direct its metabolic machinery to amalgamate novel virus particle and to diminish the ability of flu viruses to reproduce in an individual antiviral drugs are used. When used as directed, antiviral drugs may help to lessen the duration of flu symptoms and may reduce the severity of common flu symptoms. Antiviral drugs are the class of drugs which comes under the antimicrobials, and that also accommodates the larger group i.e. of antibiotics. They are broad-spectrum in nature and can be effective against a wide range of viruses. They can be used as a single drug as well as in combination of drugs. Antiviral drugs are dissimilar from the antibiotics, they do not demolish their target pathogen ideally they obstruct development of pathogen. To the greatest extent antiviral drugs currently accessible are delineate to deal with herpes viruses, covid-19, HIV, the hepatitis b and c viruses herpes simplex, small pox, picornavirus and influenza a and b viruses etc. Scientists are searching to drag out the range of antiviral to the other families of pathogens. They mainly act by inhibiting the attachment of viruses on cells, prevent genetic reproduction of virus, prevent viral protein production and vital for production of virus. The emanation of antiviral is generally the outcome about an appreciably expanded skills or proficiency of the generative, microscopic and atomic activity of organisms, allowing biomedical analyst to acknowledge the structure, mechanism of action and activity of viruses, significant progress within the procedure for come across the current drugs**.** Coronavirus 2019 (COVID 19) is highly infectious disease triggered by SARS-CoV-2 (severe acute respiratory syndrome) coronavirus 2 causing nearly 2.9 million deaths worldwide. With the emergence of SARS-CoV-2, the repurposing of antiviral drugs has come into picture.

**Keywords:** Parasitism, Broad spectrum, Genetic development of virus, Target pathogen, Viral protein production

#### **1. Introduction**

Severe Acute Respiratory Syndrome Coronavirus also known as SARS- CoV, a medical condition arises due to viral infection of SARS-CoV. It was proved to be major threat to human civilization in 21st century was declared as pandemic by World Health Organization in March 2020 as the exposure of this syndrome affected the human life cycle poorly causing deaths at an average of 10 percent

of the affected population globally. This was first emerges in the Wuhan (a state of China) in December 2019 and later on feast globally by the transmission from affected person to the other person through physical contact [1, 2] and later on when it was established and discovered, the first preventive measure was social distancing which came into force February 2020 according to WHO guidelines and other coronavirus like MERS (Middle east respiratory syndrome) in 2017 and Covid-19 which emerges before 2020.
