**6.5 TMPRSS2**

Transmembrane Serine Protease 2, TMPRSS2 presents another potential point of connection between cancer and COVID-19. In prostate cancer TMPRSS2 is regulated by the androgen receptor, and the androgen receptor is found not only on prostate cells but on cells of the lung as well. Further investigation is needed to confirm whether the receptor regulates TMPRSS2 in lung tissue, but if it does, androgen-targeted therapies, which are used in the treatment of prostate cancer, could limit SARS-CoV2 infection by downregulating TMPRSS2.
