**7. Conclusion**

Once the globe has suddenly got into the pandemic of COVID-19, all the scientific community has been making every effort to understand the etiology, pathophysiology, societal and clinical aspects of the SARS-CoV-2 viral infection all over the world. As of time this chapter is compiled, there are several vaccines developed in several countries. However, despite all the efforts, there is yet no specific and validated treatment for the infection. Instead, the medicinal products already available are being used in all clinical presentations, including antivirals, antibiotics, antimallarians, ans the agents aiming to take the disease under control. Here, taking the available published evidence in place, we elaborated the structure and pathophysiological aspects which are treatment targets to fight against the pandemic of our age. In this context the mesenchymal stem cells apear as advanced medicinal product of the cellular treatment option. Having the available knowledge refering the mechanism of action of MSCs and their safe and effective potencies at a specific disease stage makes MSCs as an ideal therapeutic candidate. Although still the data to be obtained from future the large scale randomised controlled clinical trials conduct remains an underexplored research area in the field, we suggest that under the light of the available evidence today, MSCs can be used as add-on therapy with promising effectiveness and safety to control, and even treat the COVID-19 infection with regenerative, antiinflammatory, anti-fibrotic, immunomodulatory and reparative characteristics.
