**Conflict of interest**

All authors of this chapter are employed by PerkinElmer Inc. in some capacity; however, they have no personal financial incentives in the success or failure of the company, nor was their research referenced in this chapter impacted or influenced by their employment status or any financial incentives. RJ Nash is the owner of

Jeevan BioSciences with personal financial interest in the company; however, none of the research conducted for this chapter directly benefited Jeevan BioSciences, nor did his ownership impact the research.
