**6.4 Coagulopathy**

Bleeding complications including thrombosis are leading causes of death in cancer patients. Thrombotic events are also commonly associated with the morbidities in COVID-19 patients. Cancer/tumor cells release cytokines, cysteine proteases, tumor micro particles and other pro-coagulants in their microenvironment. Release of such biomolecules can cause an imbalance in hemostasis [33]. Increased levels of D-dimer and prothrombin and decrease in fibrinogen is reported in COVID-19 nonsurvivor patients at days 10–14 [34–36]. This highlights the significance of regular monitoring and maintenance of these factors in COVID-19 and cancer patients. Therefore, further insights into the molecular interconnections of COVID-19 and cancer disease conditions to coagulopathy may help in reducing the associated mortality in these patients.
