**3. Conclusion**

Covid-19 is a devastating situation to the whole world and this infection is the reason for the morbidity and mortality of millions of people around the globe. It has shown impact on the health, economy and social aspect of the general population. Various therapeutic agents like ACE-2, TMPRSS2, JAK–STAT, cathepsin L, furin inhibitors, antiviral drugs, corticosteroids and plasma therapy have been tried for the treatment of covid-19 infected patients; however, conflicting results are obtained during the various clinical trials in the use of some therapeutic agents. Further, various vaccination programmes through various vaccine candidates are under progress; nevertheless, it will take time to complete dosing the millions of people. Therefore, various therapeutic agents are in need and require research to tackle this SARS-CoV-2 infection.
