*2.3.1 Definitions*

PG is the inherited variation study in relation to drug response. Its goal is to develop novel ways to minimize toxicity and maximize drug efficacy for the patient [34]. PG is an important innovation in clinical medicine as a result of progression of genomic science to determine the correct drug with the correct dose as a specific treatment with the use of genetic information [35]. Personalized medicine has the potential to select the most appropriate drug for certain patients, to predict optimal dosage for a drug, and to develop cost-effective treatments. Individualized response to treatment may be attributed to biological (for example age, sex, nature of disease), behavioral (for example smoking, drug interactions), or genetic factors (for example genetic variants of pharmacogenes) [34].
