**5. Limitation of the CorPath system**

Currently both the CorPath 200 and the GRX model are only compatible with 0.014-inch wires and rapid exchange delivery systems. The upcoming generations of the CorPath systems will be able to manipulate 0.035-inch wires also, which will provide better support for more challenging procedures and could broaden the area of robotic-assisted procedures.

Results of robotic-assisted peripheral vascular interventions have been presented in several regions, but the utility of this approach remains unclear in complex and different scenarios such as chronic total occlusions, severely calcified lesions or obliterative diseases affecting bifurcations. Currently there is no data available in the use of mesenteric or celiac interventions and also the system was not yet used for EVAR. Although there is a demand to perform parts of complex aneurysm procedures to reduce radiation exposure and to reduce manipulation and the number of wire-vessel wall contacts. Active control of the guiding catheters may provide a possible solution to this problem [31].

It is important to emphasize that the published trials and studies reported excellent outcomes and good intravascular navigation, the absence of haptic feedbacks may have an effect on procedural outcomes [23]. This could be an important factor, when maneuvering in smaller vessels like coronary, cerebral and visceral vessels. For this reason, the precise control over the endovascular devices is mandatory and a crucial factor of procedural success [5].
