**5. Quality of life (QoL)**

In recent times, the use of the term quality of life (QoL) has become frequent in a wide variety of contexts. Environmentalists emphasize the physical/biological environment, economists on parameters such as gross national product, doctors on symptoms, psychologists on human needs, and satisfaction. It follows that quality of life should be considered a multidisciplinary entity that is applicable and inherent to all society and the world, and its consideration by all leaders and scientists of humanity should be contemplated [9]. That is why it affirms Grau, in 1996 that the Quality-of-Life study invites us to abandon traditional positions and glimpse common sources of approach.

Almost all the authors agree that the term appears in the decade of Within Health Psychology; according to Grau, 1996, there are three large groups of problems when approaching the development of studies in Quality of Life. The first is that of its conceptual indistinctness, determined by its complex nature, the second referring to problems related to Quality of Life and the third problem inherent to the difficulties in its evaluation.

In pediatric literature, quality of life is defined as multidimensional. It includes the child's social, physical and emotional functioning and, if necessary, of his family [10]. Quality of life questionnaires have generally been validated related to health in which information from people close to children has been used; the ability of children to report their health status has not been considered adequate [11].

For a child, it is difficult to discriminate what is quality of life, since it has no source of comparison because due to its short life and the experiences it has had, it can build its concept of life, that is why on many scales to measure the quality of life of the child takes into account the perception that family members have of wellbeing in the child.

In this sense, a child's quality of life must be focused on providing a healthy environment, where they can fully develop their mental, physical and social capacities, allowing them to carry out childhood activities, reinforcing healthy beliefs that imply responsibility in their immunological condition.

#### **5.1 Quality of life factors to consider in psychoneuroimmunology**

Quality of Life is based on the construction that a person makes of their living standards according to their personal beliefs and environment, which determines their general well-being. Among the elements to consider are the following:

