**Table 1.**

*Articles regarding quality-of-life impairment in patients with skin diseases and cohabitants.*

some types of alopecia, such as alopecia areata, are not chronic and patients can be completely recovered from its disease [125].

Regarding psychological impact of patients and cohabitants, HADS-A and HADS-D are the most frequent scales used, **Table 2**. The highest rates of patient's anxiety are reported for HS (9.51) and psoriasis (8.82), followed by frontal fibrosing alopecia (7.5), acne (6.9) and alopecia areata (6.6). The highest rates of cohabitants


*HADS, Hospital Anxiety and Depression Scale; MCS-12, Mental Health Subscale; PANAS: Positive Affect and Negative Affect Schedule; PCS-12, Physical Health Subscale; SWLS: Satisfaction With Life Score; SSC: Short Stress Questionnaire.*

#### **Table 2.**

*Articles regarding psychological impairment in patients with skin diseases and cohabitants.*

anxiety are reported for psoriasis (8.06), followed by HS (7.22), acne (6.91), alopecia areata (6.5) and frontal fibrosing alopecia (4.5). Depression was rated lower than anxiety in all diseases. Patients reported the highest rates for HADS-Depression in HS (7.7) and psoriasis (6.15), followed by alopecia areata (4.9), frontal fibrosing alopecia (4.1) and acne (2.47). Cohabitants reported the highest rates for HADS-Depression in alopecia areata [6], HS (5.14), psoriasis (4.73), acne (4.23) and frontal fibrosing alopecia. Up to our knowledge, there are no reports regarding the impact of AD in cohabitants anxiety and depression. In agreement with DLQI and FDLQI scores, psoriasis and HS are the diseases that have the greatest impact on patients and cohabitants anxiety [ 6, 7, 32, 51–53]. Regarding depression, patients' reports are in agreement with anxiety and DLQI scores. Nevertheless, cohabitants reported the highest scores for anxiety in alopecia areata [124]. This might be due because most alopecia areata patients are children and their hair loss negatively affect their parent's psycho [112].
