**6. Conclusion**

Our overall findings are that there are three subtypes of ambulatory ISH (24-hour ISH, night-time ISH and daytime ISH) which had not been previously defined. Night-time ISH is the most prevalent form of ISH in this population. Most importantly our results indicate that all these ISH subtypes may be as detrimental to cardiovascular organs as hypertension as they all emerged as good predictors of elevated PWV and LVMI, which are markers of arterial stiffness and left ventricular hypertrophy respectively. This highlights the importance of using both conventional and ambulatory BP techniques for the diagnosis ISH because current strategies that are limited to conventional BP monitoring, are incapable of detecting ambulatory isolated systolic hypertension subtypes. Moreover, since this data shows that night-time ISH is the most prevalent form of ISH, and it predicts both arterial stiffness and left ventricular hypertrophy, diagnosis of nocturnal ISH may be very essential in the management of BP related cardiovascular target organ damage.

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**Author details**

*Ambulatory Isolated Systolic Hypertension and Cardiovascular Target Organ Damage in People…*

The authors would like to acknowledge Mokgadi Maseko for her technical support and members of the Soweto community whose voluntary participation made

Muzi Maseko\*, Bongubuhle Mlambo, Edgar Phukubje and Thamsanqa Nyundu

© 2021 The Author(s). Licensee IntechOpen. This chapter is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/ by/3.0), which permits unrestricted use, distribution, and reproduction in any medium,

University of the Witwatersrand, Johannesburg, South Africa

\*Address all correspondence to: muzi.maseko@wits.ac.za

provided the original work is properly cited.

*DOI: http://dx.doi.org/10.5772/intechopen.96521*

**Acknowledgements**

this study possible.

*Ambulatory Isolated Systolic Hypertension and Cardiovascular Target Organ Damage in People… DOI: http://dx.doi.org/10.5772/intechopen.96521*
