**7. Conclusion**

The responsibility of sympathetic dysfunction in the genesis or aggravation of cardiovascular and/or metabolic disorders is currently confirmed.

The consequences could vary depending on the genotypic and phenotypic characteristics of individuals and their environment, this encourages us to always explore the autonomic nervous system as part of the etiological assessment of the metabolic syndrome in general or of arterial hypertension and T2DM in particular.

The metabolic and functional consequences of ANS dysfunction could have a role not only in the genesis of T2DM but also in the development of complications and in its management.

A predominance of the sympathetic over the parasympathetic is responsible for insulin resistance, impaired insulin secretion and hyperglucagonemia, hence the importance of the exploration of the S.N.A both for screening and for management.
