**Chapter 7 101**

Humeral Artery Aneurysm Revealing a Rare Association between Tuberculosis and Behçet's Disease *by Rabie Ayari, Ramy Triki, Youssef Mallat, Achraf Abdennadher, Khalil Amri, Raja Amri and Mohamed Ali Sbai*

Preface

Tuberculosis (TB), which is caused by the infectious agent *Mycobacterium tuberculosis* (MTB), is a major global public health problem that infects one third of the world's population. However, TB is a curable and preventable disease. The World Health Organization (WHO) estimates that 10 million new cases of TB and 1.2 million deaths due to TB occurred in 2019. Globally, in 2019, close to half a million people developed rifampicin-resistant TB (RR-TB), 78% of whom had multidrug-resistant TB (MDR-TB). Molecular genotyping of MTB has been well developed over the years. This book provides an overview of the molecular epidemiology pattern, transmission dynamics, host response, evolution, and pathogenesis mechanisms of TB. It also examines mechanisms associated with increasing trends of drug-resistant TB and explores the development of anti-mycobacterial drugs. It presents updated research for policymakers and planners on diagnosis and treatment, genotyping tools, and control and prevention of MTB disease. The book also explores vigorous approaches in designing novel anti-tubercular drugs, diagnosis and treatment of latent tuberculosis infection, laboratory diagnosis via identifying novel singlenucleotide polymorphism, tracing of outbreak isolates, molecular characterization of *Mycobacterium* spp. isolated from cattle and wildlife in Poland, challenges in drug discovery against tuberculosis, and genealogy of resistant TB in Latin American

**Yogendra Shah**

Dhangadhi, Nepal

COVID-19 PCR Laboratory and Seti Provincial Hospital,

territories.
