**Funding**

processes in colloidal systems and confirmed the principle possibility of its existence by a simple mathematical model. These data allow a fresh look at the process of aggregation - disaggregation of colloidal particles in the solution. The experiments showed that the growth of water spheres pushes colloidal particles to the borders of the spheres, promotes their crowding and coagulation. On the border of water spheres, the particles form chains (reticular structures) which exist some time in liquid phase after destruction of liquid crystal water shells. Thus, all complex dynamics is controlled by the phase transitions of water – from the free to the bound (liquid crystal) state and back. Osmotic pressure acts as the intermediary messenger and the synchronizer of these transformations in a whole volume of liquid. Actually, these processes are not very sensitive to temperature (unlike the models based on calculation of Casimir forces [61–66]), and do not notably depend on liquid disturbance by hashing. Hashing by a turning of a test tube initiates emergence of streams of liquid with a characteristic size of an order of the size of a test tube (1.5 9.0 cm [53]), when the most part of the brought energy is spent for movement of spheres in bulk. Destruction of water spheres happens at initiation of microstreams of 10-100 μm in size, which correspond to the sizes of the destroyed objects. Osmotic pressure P in accordance with Eq. (3) is proportional to the absolute temperature (≈295 K). Possible changing the temperature at a few degrees is negligible to affect the considered processes. For obvious reasons parameters of fluctuations depend on concentration of the components. The described mechanism can explain some phenomena that were not clear before and deserves special research. The authors believe that we deal with a universal phenomenon of undoubted importance for fundamental and applied science. We are sure that our hypothesis will stimulate researchers with other ideas and other tool kits to join this

*Colloids - Types, Preparation and Applications*

In this chapter, the authors tried to present their ideas about the structure and dynamics of aqueous microdispersed media, which were developed by them over the course of last 20 years. The authors followed the phase transformations of the protein using the drying drop model; found similar changes in the blood serum of seriously ill people and came to the conclusion that they have a violation of the required proportion between the content of protein and salt components of blood serum; found confirmation of our conclusions in the practical activities of Dr. A.S. Samokhotskiy, who drew the attention to the importance of the problem posed and the prospects of its solution for the drug-free treatment of patients. It has been shown that water and aqueous solutions of salts are also microdispersions. There is no clean water in the world around us. Using instant coffee as an example, we made sure that aqueous dispersions live in their own rhythm, the parameters of which depend on the ratio of the volume of the dispersed phase and the ionic strength of the dispersion medium. These parameters do not depend on the volume and shape of the vessel, as well as on mechanical disturbances. Surfactants reduce the amplitude of oscillations without significantly affecting their phase. In phase with the fluctuations in the mechanical properties of dispersion media, their surface tension and the width of the edge ridge of the drops dried on glass change. The authors associated these processes with the phenomenon of aggregation - disaggregation of the dispersed phase, the elementary unit of which is a hydrophilic microparticle surrounded by a hydration shell of liquid crystalline water. A model of selfoscillatory processes in microdispersed systems, which consistently describes the

direction of study.

**5. Concluding remarks**

observed phenomena, was proposed.

**116**

This project was funded by the Ministry of Education and Science of Russia (project no 14.Y26.31.0022).
