**4.3 Properties**

Become aware of a difference in the properties of a unique sample or two sample which in principle, are to be identical is the commencement of most *polymorphism* studies. One important aspect to be considered, sometimes careless, is the manipulation of the samples before the measurements. It is widely reported that a routinely sample treatment as grinding can undergone phase transformation. Even this subtle stimulus can provoke changes in the sample with the consequent incongruent results, thus hampering their correct analysis. These changes produced by polymorphic modifications could range from slight differences to dramatic alterations of the target properties and those which have raised more interest are listed in **Figure 5**.
