*4.2.1 The first pattern: "blood stasis with Qi deficiency"*

The *Qi deficiency* is more specifically related to "*Spleen Qi deficiency*", leading to "Blood Stasis". The main TCVM principles are to improve blood circulation, nourish the blood, resolve the stagnation or accumulation, tonify the spleen, and relieve pain. Refer to **Table 4**; acupuncture on specific points can improve and enhance the symptoms described earlier. *Xiao Yao San*, which is compounded by various herbs, is a transitional Chinese medicine described in the "Formulary of the Tai Ping Welfare Dispensary Bureau' Collections of Medicinal Formulations" compiled by Chen Shi-wen et al. in 1151. A modified herb formula of *Nei Xiao Wan*, called "Stasis Breaker", has been introduced by *Xie* et al. specifically for animals [19, 32] to reduce phlegms and stasis, clear toxin substances, and promote *Qi* and *Blood* circulation. The significant effect of "Stasis Breaker" breaks the blood stasis, softening the hard nodes and tumors. Furthermore, some studies prove that *Bai Hua She She Cao* and *Ban Zhi Lian* can inhibit cell mutation, tumor growth and clear the "heat-toxin" [19, 33, 34].

### *4.2.2 The second pattern of liver carcinoma: "blood stasis with Yin deficiency"*

Heat and liver stagnation are supposed by TCVM to result in *Qi* and *Blood* stagnation. The consumption of fluid will injure the *Yin* in the *Middle Burn*. Once *Liver Yin* and *Kidney Yin* are injured, the tumor will be gradually formed. This treatment pattern focuses on nourishing *Yin* and *Blood*, resolving pain and stagnation, tonifying *Qi*, and resolving tumor. The recommended acupuncture points are shown in **Table 4**. [35]. *Yi Guan Jain*, a herbal medicine, described in the "Supplement to the Classified Case Records of Famous Physicians" by *Wei Zhi-Xiu* in 1770. It is intended to tonify the *Liver's* and *Kidney's Yin* and clear the "false heat". The combination of *Yi Guan Jain* and "Stasis breaker" effectively improves the immune system


**171**

**Author details**

and Chao-Hsun Chuang1,2,5\*

synergistic curing effect.

Chih-Feng Chen1,2,3, Shao-Wen Chiu1,2,4, Lung-Kwang Pan1

3 Yong-Shin Animal Hospital, Takun, Taichung, Taiwan, ROC

and Technology, Takun, Taichung, Taiwan, ROC

Technology, Xiang-shan, Hsin-chu, Taiwan, ROC

Integrated Systems Inc., Taipei, Taiwan, ROC

provided the original work is properly cited.

5 Chyun-Min Animal Hospital, Chunan, Taiwan, ROC

1 Graduate Institute of Radiological Science, Central Taiwan University of Science

4 Healthcare Technology Business Division, Healthcare Department, International

\*Address all correspondence to: lkpan@ctust.edu.tw and petslovers@yahoo.com.tw

© 2021 The Author(s). Licensee IntechOpen. This chapter is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/ by/3.0), which permits unrestricted use, distribution, and reproduction in any medium,

2 Bachelor Degree Program in Pet Healthcare, Yuan-Pei University of Medical

\*

*Canine Hepatic Carcinoma: Diagnoses and Treatments Via Global State-of-the-Art Approach…*

performance, inhibiting tumor growth, mutation, and metastasis. This combination can also mitigate chemotherapy/radiotherapy side-effects and improve life

The global veterinary medicine is widely used to eliminate canine carcinogens by substantiated combinations of drug administration, surgery, chemotherapy, and radiotherapy treatments. However, their side-effects remain a challenging issue faced by clinical veterinarians and dog owners. In this respect, traditional Chinese veterinary medicine (TCVM), including acupuncture, herbs, food therapy, and massage, is considered a lucrative integrated treatment system. Using the pattern differentiation, as well as the proposed biokinetic Ga-67 model of canine liver carcinoma, the robust HCC diagnosis of canine patents can be obtained. A further application of global state-of-the-art and/or TCVM-based therapies can enhance the immune system, speed up the recovery, relieve pain syndrome, reduce chemotherapy toxicities, and improve quality of life of canine patients. Thus, the global integrative oncology comprehensively combines regulated clinical treatments with complementary and alternative medicine (TCVM in particular), yielding the

*DOI: http://dx.doi.org/10.5772/intechopen.96077*

quality [12, 19, 21, 22].

**5. Conclusions**

#### **Table 4.** *TCVM acupuncture points for tumor.*

*Canine Hepatic Carcinoma: Diagnoses and Treatments Via Global State-of-the-Art Approach… DOI: http://dx.doi.org/10.5772/intechopen.96077*

performance, inhibiting tumor growth, mutation, and metastasis. This combination can also mitigate chemotherapy/radiotherapy side-effects and improve life quality [12, 19, 21, 22].
