**Author details**

*Canine Genetics, Health and Medicine*

**6.4 Molecular biology diagnosis**

**7. Treatment of infected dogs**

undertook the control of the disease.

**8. Prevention**

prevention [7].

intestine [33].

**9. Conclusion**

zoonosis is strongly advised.

prevalence of cystic echinococcosis is low [29].

Parasite DNA can be obtained from eggs, proglottis or worm cells and can be detected in feces after PCR amplification. However, no copro-PCR is currently available for the detection of all strains of *Echinococcus granulosus*; PCR primers for G1, G5 and combined G6/7 strains have been developed. This technique, due to its high cost, is only used for confirmation on positive samples in areas where the

Praziquantel is the only drug without significant undesirable effects known to be effective against *E. granulosus*. With a dose of 5 mg/kg, it can indeed achieve 100% efficacy [30, 31]. Because of its very broad therapeutic index, praziquantel is particularly suitable for cystic echinococcosis control programs [32]. Indeed, after its introduction in 1977, it was widely used in the majority of programs that

Regular and accentuated treatment of stray dogs is necessary. However, regular treatment of owned dogs with Praziquantel should be an obligation in highly endemic areas, as treatment of dogs remains the most effective measure of

Vaccination of dogs with two recombinant proteins, EgA31 isolated from the adult worm and oncosphere and EgTrop isolated from protoscolex, is a promising approach to limiting the development of the *E. granulosus* worm in the dog's

In the case of zoonotic diseases, preventive veterinary treatments allow the protection of the public and animal health, but also the reduction of the risk of their transmission to humans, as is the case for cystic echinococcosis. To be effective, these treatments must be applied regularly. Thus, facility of access to them must be taken into account when developing the canine population management program. However, it should be noted that it is not only the dog that needs to be controlled, but also the intermediate host, and efforts should be made to eliminate the parasite or pathogen in general from the intermediate host that represents the main source of transmission to the dog to allow the pathogen to complete its life cycle and become infectious. Therefore the need for an integrated approach (action on the different hosts involved in the life cycle of the pathogen and the involvement of the socio-economic factor in control programs including stakeholders) to control these

**86**

Fatima Ezzahra Amarir1 \*, Abdelmohcine Aimrane2 and Abdelkbir Rhalem1

1 Laboratory of Parasitology, Department of Pathology and Veterinary Public Health, Hassan II Agronomy and Veterinary Institute (IAV), Rabat, Morocco

2 Biochemistry Laboratory/Metabolic Platform, Cadi Ayyad University, Faculty of Medicine and Pharmacy, Marrakech, Morocco

\*Address all correspondence to: amarir.f@gmail.com

© 2021 The Author(s). Licensee IntechOpen. This chapter is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/ by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
