**2.7 Statistical analysis**

All values in this text are expressed as mean ± standard error mean (SEM). Differences between two groups were determined using Student's paired dependent t-test and were considered significant at P < 0.05. All statistical analyses were conducted using Microsoft Excel and GraphPad Prism version 8.0.1, GraphPad Software. Light microscopic micrographs were obtained on a Leica Microsystems, LAS version 4.4.0.
