Biomedical Uses of Silver Nanostructures

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**Chapter 5**

**Abstract**

Applications

**1. Introduction**

Nanoparticles

Biomedical Applications of Silver

Nanotechnology is a branch of science and engineering dedicated to materials, having dimensions in the order of nanometer scale and it has been widely used for the development of more efficient technology. Nanoparticles offer many benefits to bulk particles such as increased surface-to-volume ratio, and increased magnetic properties. In recent years, nanotechnology has been embraced by industrial sectors due to its applications in the field of electronic storage systems, biotechnology, magnetic separation and pre concentration of target analytes, targeted drug delivery, and vehicles for gene and drug delivery. Over the year's nanomaterials such as nanoparticles, nanoclusters, nanoreods, nanoshells, and nanocages have been continuously used and modified to enable their use as a diagnostic and therapeutic agent in biomedical applications. Thus, In this chapter, introduction to metal nanoparticles, synthesis (Chemical and green synthesis) and biomedical application silver nanoparticles are presented.

**Keywords:** Green Synthesis, Metal Nanoparticles , Silver nanoparticles , Biomedical

The trend of miniaturization combined with technological modernization requirements has led to the substantial rise in exploring nanoparticles. The discoveries of new antibiotics, conventional drugs and chemically modified drugs can not only resolve the microbial resistant issues but also necessitates a prolonged effective metallic nanotechnology in diverse applications. Nanomaterials such as nanoparticles, nanoclusters, nanorods, nanoshells, and nanocages are modified constantly to enable their use as a diagnostic and therapeutic agents applications. Theefficacy of the nanoparticle can be determined by its size, structure, concentration, dimensions and ionic strength accompanied with surface coating can support additional strength and durability as a carrier for a wide range of therapeutic components in several biomedical applications. Nanoparticles offer various benefits to bulk particles with increased surfaceto-volume ratio, magnetictarget [1, 2], wound healing properties [3], biocomposite

Nanoparticles synthesis and characterization have flourished due to their wideranging applicability particularly as catalysts in biomedical, optics, and energy fields [5]. Among the classified nanoparticles, metalnanoparticles have fascinated, due to their distinctive physical and chemical properties, selectivity, highly active, and reproducibility. Among different metal nanoparticles, silver nanoparticles (AgNPs) have attracted considerable researcher's attention because of its high electrical

preparation, gene and drug delivery vehicles [1, 2, 4].

*Manikandan Dhayalan, Priadharsini Karikalan,* 

*Mohammed Riyaz Savaas Umar and Nalini Srinivasan*

## **Chapter 5**
