**Author details**

Lyubomir Lazov\*, Risham Singh Ghalot and Edmunds Teirumnieks Rezekne Academy of Technology, Latvia

\*Address all correspondence to: lyubomir.lazov@rta.lv

© 2021 The Author(s). Licensee IntechOpen. This chapter is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/ by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

**123**

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**Author details**

Rezekne Academy of Technology, Latvia

provided the original work is properly cited.

\*Address all correspondence to: lyubomir.lazov@rta.lv

Lyubomir Lazov\*, Risham Singh Ghalot and Edmunds Teirumnieks

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**129**

**Chapter 8**

**Abstract**

Silver Nanoparticles Impregnated

and Future Challenges

*Jaijeet Singh, Nitish Kumar, Neena Bedi* 

*and Preet Mohinder Singh Bedi*

challenges in wound management.

wound dressing

**1. Introduction**

*Atamjit Singh, Kirandeep Kaur, Komalpreet Kaur,* 

Microbial infection remains all time and unresolved challenge in the management of burns and diabetic wounds. Especially in diabetic wounds infections are prominent reason of amputations. Microbial biofilms pose tough polymeric barrier that is difficult to cross by conventional antibiotics. Therefore, traditional approach of infection control using antibiotics is now failing at some extent that raised a need to shift this paradigm. Presently, silver nanoparticles incorporated scaffolds representing a new concept of nanoparticle dressings which is becoming popular in wound management. Recently developed silver nanoparticles functionalized wound dressings exhibited excellent profile in the management of wound infections and promotion of wound healing. This chapter throw light on the recent strategies used in the development of silver nanoparticles functionalized wound dressings and their outcomes along with potential benefits and future

**Keywords:** Silver nanoparticles, wound infections, biofilms, diabetic wounds,

A wound is any type of injury which can be in the form of a cut, bruise or contusion caused by some external force. Open wounds are susceptible of getting infected by microorganisms like bacteria, virus or fungi if left unattended. Infected wounds pose a major challenge for healthcare system due to its direct relation with mortality and morbidity of the affected patients [1]. When a wound is infected it causes stress (physiological and psychological) and slows down the wound healing process and in some cases worsens the situation [2]. Approximately 2% of all hospitalized patients worldwide have a chronic wound, and older adult patients are at highest risk, because aging impairs the healing process [3, 4]. As many as 70% of these wounds recur, and 34% are accompanied by infection [5]. A survey by Medicare beneficiaries in 2018 stated that approximately 8.2 million individuals were having some kind of wounds, with or without infection and they estimated the treatment cost to be near about 28.1 billion to 96.8 billion dollars making it a big

Wound Dressings: Recent Progress

**Chapter 8**
