**1. Introduction**

Our contribution to the open access book of palliative care focuses on specific and severe symptoms resulting from affected abdominal and pelvic organs and feminine genitals. These symptoms are mainly connected to advanced gynaecologic malignancies. Patients with locally advanced or recurrent gynaecologic cancers may present with various symptoms. Among those we discuss vaginal bleeding, vaginal discharge and fistulas. Problematics of pain control, oedema and ascites, nausea and vomiting, shortness of breath and malignant bowel obstruction is common to most incurable advanced diseases and these are not connected to pelvic diseases only, see specific chapters. Vice versa non-malignant diseases and nonpelvic site diseases such as inflammations, overdose of anticoagulants, wounds or pressure ulcers may have similar clinical manifestation. Some symptoms may result from aggressive cancer treatment (oncological surgery, radiotherapy) with curative intent. Some symptoms get worse on account of the postmenopausal status (natural or artificial following any type of ovarian failure). For advanced gynae-oncological diseases it has been in practise, that the best palliative care is

offered and practised simultaneously with curative treatment. Optimum palliative care can only be provided by a team that may include a gynaecologic oncologist, a radiation oncologist, an interventional radiologist, a palliative care physician, nurse and a social worker to address the various problems faced by these patients [1, 2]. All described clinical situations can be well solved in hospices as well as at patient's home with the guidance of experienced mobile palliative care teams. Except for malignant bowel obstruction and severe genital bleeding, which both present extreme mental and physical load for the caregivers who witness it and it can be traumatizing experience for unprepared family members and healthcare providers.
