**6. Conclusion**

As a result, oxidative stress can cause serious damage to the cell. Thiol is a very important antioxidant in preventing oxidative stress-induced damage and protects the cell against oxidative stress. Glutathione and taurine are among the important thiols. It is observed that thiol status changes in various diseases and thiol/disulphide homeostasis is very important in the pathogenesis of various diseases such as digestive system, respiratory system, reproductive system, urinary system, metabolic diseases and cancer. This also shows that thiol state is very important in the pathogenesis of oxidative stress-mediated diseases. Therefore, it is thought that interventions that can improve thiol status may contribute to the prevention or treatment of oxidative stress-related diseases.
