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## Meet the editor

Dr. Xingshun Qi obtained his medical doctoral degree at the Fourth Military Medical University and completed his post-doctoral fellowship at the General Hospital of Shenyang Military Area, China. Currently, he is a deputy director at the Department of Gastroenterology at General Hospital of Northern Theater Command (formerly General Hospital of Shenyang Military Area). His major research interests are the management of liver

cirrhosis, portal hypertension (especially portal vein thrombosis and Budd-Chiari syndrome), and hepatocellular carcinoma. He has edited six English-language books and serves as an associate editor for *BMC Gastroenterology*, an academic editor for the *Canadian Journal of Gastroenterology and Hepatology*, and an advisory editorial member of *Advances in Therapy*. His H-index is 37 with 4467 citations to date.

Contents

**Section 1**

*by Achyut Bikram Hamal*

*by Reda A. Zbaida*

**Section 2**

**Section 3**

Pediatric Portal Hypertension

Sinusoidal Obstruction Syndrome

and Progression of Portal Hypertension

*by Ran Wang, Xiaozhong Guo and Xingshun Qi*

Endoscopy in Management of Portal Hypertension

*by Elena Curakova Ristovska*

with Portal Hypertension

**Preface XI**

Overviews of Portal Hypertension **1**

**Chapter 1 3**

**Chapter 2 25**

**Chapter 3 39**

Pathogenesis of Portal Hypertension **55**

**Chapter 4 57**

Non-Invasive Assessment and Endoscopy in Portal Hypertension **79**

**Chapter 5 81**

**Chapter 6 91**

*by Yanxia Fei, Yanhua Peng, Huiping Sun, Shuangfa Zou and Jinfeng Yang*

Endothelial Dysfunction and Systemic Inflammation in the Pathogenesis

Non-Invasive Prediction of Gastroesophageal Varices in Patients

*by Bhavik Bharat Shah, Usha Goenka and Mahesh Kumar Goenka*

Brief Review of Portal Hypertension Related Complications

## Contents


Preface

Portal hypertension is a rise in the pressure gradient between the portal vein and the inferior vena cava. Realistically, it is difficult to directly measure the portal vein pressure. For this reason, hepatic venous pressure gradient, which can be calculated by subtracting wedged hepatic vein pressure from free hepatic vein pressure, has been employed in clinical practice to establish a diagnosis of portal hypertension. There are various types of portal hypertension, including pre-hepatic, hepatic, and post-hepatic. Nowadays, the management of portal hypertension and its

This book, *Portal Hypertension - Recent Advances* does not intend to cover all areas of management of portal hypertension, but rather focuses on the recent advances in several major topics, including pediatric portal hypertension, sinusoidal obstructions syndrome, endoscopy in the management of portal hypertension, and non-invasive assessment of esophageal varices. These topics should be interesting and helpful for gastroenterologists, hepatologists, endoscopists, and pediatricians interested in

Finally, I greatly appreciate the contributions from the chapter authors and the

**Xingshun Qi**

Shenyang, China

Department of Gastroenterology,

General Hospital of Northern Theater Command,

assistance from Josip Knapić, Author Service Manager at IntechOpen.

complications is still a clinical challenge.

this field.
