**6. Conclusion**

Nearly 15 years after first being described, laparoscopic liver resection has been gradually gaining acceptance in a number of centers worldwide. As the necessary skills in advanced laparoscopy and hepatic surgery become more widespread, we anticipate that the further adoption of laparoscopic liver resection will increase more rapidly. The maturation of long term series have proven the oncologic adequacy of the laparoscopic approach in a variety of settings. With the development of a greater number of surgeons who are proficient in laparoscopic liver surgery, many more patients will benefit from decreased blood loss, less postoperative pain, and shorter lengths of stay. From being a novel procedure practiced in only a handful of centers worldwide, laparoscopic liver resection is now established as a

Laparoscopic Liver Resection 75

House, MG et al Survival after hepatic resection for metastatic colorectal cancer: trends in

Hsu, TC Intra-abdominal lesions could be missed by inadequate laparoscopy

Imamura, H et al One thousand fifty-six hepatectomies without mortality in 8 years

Johnstone, PA et al Port site recurrences after laparoscopic and thoracoscopic procedures in

Koffron, AJ et al Laparoscopic liver surgery for everyone: the hybrid method Surgery2007;

Lai, EC et al Minimally invasive surgical treatment of hepatocellular carcinoma: long-term

Laurent, A et al Laparoscopic liver resection facilitates salvage liver transplantation for hepatocellular carcinoma J.Hepatobiliary.Pancreat.Surg.2009;16(3):310-314 Lefor, AT & Flowers, JL Laparoscopic wedge biopsy of the liver J.Am.Coll.Surg.1994;

Liang, TB et al Intraoperative blood salvage during liver transplantation in patients with

Martin, RC et al Simultaneous versus staged resection for synchronous colorectal cancer

Micchelli, ST et al Malignant transformation of hepatic adenomas Mod.Pathol.2008;

Motohara, T et al MR imaging of benign hepatic tumors Magn Reson.Imaging

Nguyen, KT et al World review of laparoscopic liver resection-2,804 patients Ann.Surg.2009;

Pawlik, TM et al Effect of surgical margin status on survival and site of recurrence after hepatic resection for colorectal metastases Ann.Surg.2005;241(5):715-22, discussion Rahbari, NN et al Hepatocellular carcinoma: current management and perspectives for the

Reshamwala, PA et al Nodular regenerative hyperplasia: not all nodules are created equal

Rooks, JB et al Epidemiology of hepatocellular adenoma. The role of oral contraceptive use

Seki, S et al A clinicopathological study of inflammatory pseudotumors of the liver with special reference to vessels Hepatogastroenterology2004;51(58):1140-1143 Semelka, RC et al Focal liver lesions: comparison of dual-phase CT and multisequence

Sturtz, CL & Dabbs, DJ Angiomyolipomas: the nature and expression of the HMB45 antigen

multiplanar MR imaging including dynamic gadolinium enhancement J.Magn

hepatocellular carcinoma: efficiency of leukocyte depletion filters in the removal of

J.Am.Coll.Surg.2010; 210(5):744-745

Arch.Surg.2003;138(11):1198-1206

malignancy J.Clin.Oncol.1996;14(6):1950-1956

outcome World J.Surg.2009;33(10):2150-2154

tumor cells Transplantation2008;85(6):863-869

liver metastases J.Am.Coll.Surg.2009;208(5):842-850

Mortele, KJ & Ros, PR Benign liver neoplasms Clin.Liver Dis.2002;6(1):119-145

Paradis, V Benign liver tumors: an update Clin.Liver Dis.2010;14(4):719-729 Parkin, DM et al Global cancer statistics, 2002 CA Cancer J.Clin.2005;55(2):74-108

Am.Surg.2008;74(9):824-826

142(4):463-468

178(3):307-308

21(4):491-497

250(5):831-841

Clin.N.Am.2002;10(1):1-14

Hepatology2006;44(1):7-14

JAMA1979;242(7):644-648

Reson.Imaging2001;13(3):397-401

Mod.Pathol.1994;7(8):842-845

future Ann.Surg.2011;253(3):453-469

outcomes for 1,600 patients during two decades at a single institution

safe and effective technique in the therapeutic decision tree for patients with surgical disease of the liver. We believe that this acceptance will continue to grow to the point that the laparoscopic approach will, as has been seen with colon resection, eventually be adopted as the standard of care in appropriately selected patients.
