**8. References**


In conclusion laparoscopic incisional hernia repair is feasible and safe. Reduced SSI and reduced hospital stay are the major short term advantages associated with laparoscopy most likely as a consequence of reduced wound size [18, 27]. Recurrence rate are comparable in

[1] M. Korenkov and E. Neugebauer. (2001). Comments on the letter from S. Petersen and K.

[2] K. Cassar and A. Munro. (2002). Surgical treatment of incisional hernia. *Br J Surg,* Vol.

[3] M. Mudge and L. E. Hughes. (1985). Incisional hernia: a 10 year prospective study of

[4] J. Hoer, G. Lawong, U. Klinge and V. Schumpelick. (2002). [Factors influencing the

[6] F. C. Usher. (1962). Hernia repair with Marlex mesh. An analysis of 541 cases. *Arch Surg,*

[7] V. Schumpelick, J. Conze and U. Klinge. (1996). [Preperitoneal mesh-plasty in incisional

[8] K. A. LeBlanc. (2005). Incisional hernia repair: laparoscopic techniques. *World J Surg,* Vol.

[9] F. E. Muysoms, M. Miserez, F. Berrevoet, G. Campanelli, G. G. Champault, E. Chelala,

[10] J. Nieuwenhuizen, G. H. van Ramshorst, J. G. Ten Brinke, T. de Wit, E. van der Harst,

[11] A. Kurmann, E. Visth, D. Candinas and G. Beldi. (2011). Long-term follow-up of open

[12] A. Kurmann, G. Beldi, S. A. Vorburger, C. A. Seiler and D. Candinas. (2010).

patients over a period of 10 years]. *Chirurg,* Vol. 73, No. 5, pp.474-480, [5] L. T. Sorensen, U. B. Hemmingsen, L. T. Kirkeby, F. Kallehave and L. N. Jorgensen.

Ludwig concerning our paper "Classification and surgical treatment of the incisional hernia. Results of expert meeting." Langenbeck's Arch Surg 386:65-73.

development of incisional hernia. A retrospective study of 2,983 laparotomy

(2005). Smoking is a risk factor for incisional hernia. *Arch Surg,* Vol. 140, No. 2,

hernia repair. A comparative retrospective study of 272 operated incisional

U. A. Dietz, H. H. Eker, I. El Nakadi, P. Hauters, M. Hidalgo Pascual, A. Hoeferlin, U. Klinge, A. Montgomery, R. K. Simmermacher, M. P. Simons, M. Smietanski, C. Sommeling, T. Tollens, T. Vierendeels and A. Kingsnorth. (2009). Classification of primary and incisional abdominal wall hernias. *Hernia,* Vol. 13,

W. C. Hop, J. Jeekel and J. F. Lange. (2011). The use of mesh in acute hernia:

and laparoscopic repair of large incisional hernias. *World J Surg,* Vol. 35, No. 2,

Laparoscopic incisional hernia repair is feasible and safe after liver transplantation.

**7. Conclusion** 

**8. References** 

laparoscopic and open incisional hernia repair [18].

89, No. 5, pp.534-545,

Vol. 84, No. pp.325-328,

29, No. 8, pp.1073-1079,

No. 4, pp.407-414,

pp.297-301,

pp.119-123,

*Langenbecks Arch Surg,* Vol. 386, No. 4, pp.310-311,

hernias]. *Chirurg,* Vol. 67, No. 10, pp.1028-1035,

frequency and outcome in 99 cases. *Hernia,* Vol. No.

*Surg Endosc,* Vol. 24, No. 6, pp.1451-1455,

incidence and attitudes. *Br J Surg,* Vol. 72, No. 1, pp.70-71,


**Part 5** 

**Laparoscopic Solid Organ Surgery** 


**Part 5** 

**Laparoscopic Solid Organ Surgery** 

192 Updated Topics in Minimally Invasive Abdominal Surgery

[27] M. S. Sajid, S. A. Bokhari, A. S. Mallick, E. Cheek and M. K. Baig. (2009). Laparoscopic

[28] G. Beldi, R. Ipaktchi, M. Wagner, B. Gloor and D. Candinas. (2006). Laparoscopic

197, No. 1, pp.64-72,

92-95,

versus open repair of incisional/ventral hernia: a meta-analysis. *Am J Surg,* Vol.

ventral hernia repair is safe and cost effective. *Surg Endosc,* Vol. 20, No. 1, pp.

**12** 

*P.R. China* 

**Spleen Preserving Surgery and** 

Lianxin Liu, Dalong Yin and Hongchi Jiang

*Department of Hepatic Surgery,* 

**Related Laparoscopic Techniques** 

*The First Affiliated Hospital of Harbin Medical University, Key Laboratory of Hepatosplenic Surgery, Ministry of Education, Harbin, Heilongjiang Province* 

"The spleen" whose weight once thought to have been hindering the speed of runners to its role in cleansing process as its absence could result in the loss of laughing ability was called the "mysteriipleniorganon". Its biological function has been elusive for thousand of years and also had been assumed to have no vitality in life. It's been centuries since its existence has been under tremendous perusal and it wasn't until mid-twelfth century when the concept of blood purifying function was emphasized. In early 1900, however, numerous experiments have concluded its role in the host defense and immune function. Spleen surgery dates back to 1549. Zaccaelli carried out the first splenectomy in this year. In 1952, King and Schumaker reported the overwhelming postsplenectomy infection (OPSI) in children with hereditary spherocytosis who had undergone splenectomies, which caused a

The spleen richly contains T cells, B cells, K cells, macrophages/monocytes, natural killer cells, killer cells, lymphokine-activated killer (LAK) cells, dendritic cells and so forth, and in conjunction with a variety of immune factors to makes in vivo immune response. Tuftsin is a tetrapeptide produced by the spleen to stimulatepha- gocytosis through the activation of neutrophils, it is a typical anti-tumor substance in the spleen, and can reflect the spleen function. Spleen tyrosine kinase (SYK) is a non-receptor tyrosine kinase, initially expressed in the spleen hematopoietic cells. SYK plays an important role in the Fc-mediated phagocytosis, B cell receptor signal transduction, cytokine secretion, and integrin-mediated

Weiss first proposed in 1986 that there is a blood-spleen barrier (BSB) between the artery and vein in the spleen, which is similar to blood-brain barrier and can filter Plasmodium falciparum-infected red blood cells. Jiang and Zhu et al respectively made their study on rat spleens and set up the concept and architecture of the BSB: The blood-spleen barrier (BSB) is located in the marginal zone of the spleen, which lies at the periphery of the white pulp;

**1. Introduction** 

**2. Splenic function** 

signal transduction. **Barrier function** 

**Immunity** 

wide concern on the potential function of the spleen.
