**3.8 Protein adsorbed study**

The adsorption of protein on a wound dressing film indicates its cell adhesion behavior. Albumin, a multifunctional transporter protein, is the most abundant protein found in the plasma (approx. 50 mg.ml−1) [31]. Its adsorption is related to the inhibition of the coagulation cascade and consequently, platelet adsorption. As per reports [32], albumin has high adsorption affinity for hydrophobic surfaces,

**105**

and 14.1 mg/m<sup>2</sup>

**Figure 7.**

*at 37o C.*

**Figure 6.**

It has been reported [33] (**Figure 8**).

*Wound Dressing Application of Ch/CD Nanocomposite Film*

*d/do (versus time profiles for the samples) Ch/CD (0) and Ch/CD(2) at 37o*

mainly because of hydrophobic interactions between the protein and the surface. Indeed, a wound dressing film with a poor tendency to adsorb albumin is desirable.

*BSA adsorption on the various samples Ch/CD (0), Ch/CD (1), Ch/CD (2), Ch/CD (3) and Ch/CD (4)* 

It can be seen that plain sample Ch/CD(0), and CDs-loaded samples Ch/CD(1), Ch/CD(2), Ch/CD(3) and Ch/CD(4) show BSA adsorption of 24.2, 21.5, 18.3, 15.9

indicative of the hydrophilic nature of the film surfaces for all the samples studied.

In this work, % scavenging capacity of the plain film sample Ch/CD(0) and carbon dots loaded samples Ch/CD(1), Ch/CD(2), Ch/CD(3) and Ch/CD(4) for the various free radicals i. e. DPPHR, SOR and HR are shown in **Figure 9**. It can be seen

respectively. The extremely low values of BSA adsorption may be

 *C.*

The results of BSA adsorption study are shown in **Figure 7**.

**3.9 Antioxidant properties of hydrogel wound dressings**

*DOI: http://dx.doi.org/10.5772/intechopen.95107*

**Figure 6.** *d/do (versus time profiles for the samples) Ch/CD (0) and Ch/CD(2) at 37o C.*

**Figure 7.** *BSA adsorption on the various samples Ch/CD (0), Ch/CD (1), Ch/CD (2), Ch/CD (3) and Ch/CD (4) at 37o C.*

mainly because of hydrophobic interactions between the protein and the surface. Indeed, a wound dressing film with a poor tendency to adsorb albumin is desirable. The results of BSA adsorption study are shown in **Figure 7**.

It can be seen that plain sample Ch/CD(0), and CDs-loaded samples Ch/CD(1), Ch/CD(2), Ch/CD(3) and Ch/CD(4) show BSA adsorption of 24.2, 21.5, 18.3, 15.9 and 14.1 mg/m<sup>2</sup> respectively. The extremely low values of BSA adsorption may be indicative of the hydrophilic nature of the film surfaces for all the samples studied. It has been reported [33] (**Figure 8**).
