**3. References**


[6] M. Derouich, A. Boutayeb, The effect of physical exercise on the dynamics of glucose

[7] Diabetes Control and Complications Trial Research Group, The effect of intensive

[8] T.M. Gross, D. Kayne, A. King, C. Rother, S. Juth, A bolus calculator is an effective

[9] A.P. Harmel, R. Mathur, Davidson's Diabetes Mellitus: Diagnosis and Treatment, fifth

[10] W.B. Saunders, A.E. Kitabchi, J.N. Fisher, G.A. Burghen, M.S. Gaylord, N.M. Blank,

[11] R. Linkeschova, M. Raoul, U. Bott, M. Berger, M. Spraul, Less Severe hypoglycemia,

[12] R.S. Parker, F.J. Doyle, N.A. Peppas, A model-based algorithm for blood glucose control in type I diabetic patients, IEEE Trans. BioMed. Eng. 46 (1999) 148–157. [13] L. Perko, Differential Equations and Dynamical Systems, Springer-Verlag, New York, 1996. [14] J.C. Pickup, M.C. White, H. Keen, J.A. Parsons, K.G. Alberti, Long-term continuous subcutaneous insulin infusion in diabetics at home, Lancet 2 (1979) 870–873. [15] J. Pickup, H. Keen, Continuous subcutaneous insulin infusion at 25 years: evidence

[16] G. Pillonetto, G. Sparacino, C. Cobelli, Numerical non-identifiability regions of the

[17] W. Regittnig, Z. Trajanoski, H.J. Leis, M. Ellmerer, A. Wutte, G. Sendlhofer, L.

dynamics after intravenous glucose injection, Diabetes 48 (1999) 1070–1081. [18] Report of the expert committee on the diagnosis and classification of diabetes mellitus,

[19] The UK Prospective Diabetes Study (UKPDS) Group, Intensive blood glucose control

[20] G. Toffolo, E. Breda, M.K. Cavaghan, D.A. Ehrmann, K.S. Polonsky, C. Cobelli,

[24] Himsworth/ H. 1. and 5er/ R. B./ Insulin sensiti<e and insulin insensiti<e types of

treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus, New. Engl. J. Med. 329 (1993)

means of controlling postprandial glycemia in patients on insulin pump therapy,

Evaluation of a portable insulin infusion pump for outpatient management of

better metabolic control and improved quality of life in type 1 diabetes mellitus with continuous subcutaneous insulin infusion (CSII) therapy; an observational study of 100 consecutive patients followed for a mean of 2 years, Diabetes Med. 19

base for the expanding use of insulin pump therapy in type 1 diabetes, Diabetes

minimal model of glucose kinetics: superiority of Bayesian estimation, Math.

Schaupp, G.A. Brunner, P. Wach, T.R. Pieber, Plasma and interstitial glucose

with sulphonylureas or insulin compared withconventional treatment and risk of complications in patients with type 2 diabetes (UKPDS33), Lancet 352 (1998) 837–853.

Quantitative indexes of b-cell function duringgraded up and down glucose infusion from C-peptide models, Am. J. Physiol. Endocrinol. Metab. 280 (2001) E2–E10. [21] I.M. Tolic´, E. Mosekilde, J. Sturis, Modelling the insulin–glucose feedback system: the significance of pulsatile insulin secretion, J. Theor. Biol. 207 (2000) 361–375. [22] J. Unger, A primary care approach to continuous subcutaneous insulin infusion, Clin.

and insulin, J. Biomech. 35 (2002) 911–917.

Diabetes Technol. Ther. 5 (2003) 365–369.

brittle diabetes, Diabetes Care 2 (1979) 421–424.

977–985.

ed., 2004.

(2002) 746–751.

Care 25 (2002) 593–598.

Biosci. 184 (2003) 53–67.

Diabetes Care 20 (1997) 1183–1197.

Diabetes 17 (1999) 113–127.

[23] Management of Type 2 Diabetes, N ENGL J MED 358;3, 2008.

diabetes mellitus/ Clinical Science/ 4 D1F3FH 11F.
