**c.Red seaweeds**

The red seaweeds have been widely studied to elucidate the inhibitory effect on angiotthe ensin-converting enzyme, as it plays a crucial role in regulating blood pressure. According to the recorded studies, the aqueous extract at 20 °C of red seaweeds *Lomentaria catenata, Lithophyllum okamurae, Ahnfeltiopsis flabelliformis, and Gracilaria textorii* significantly inhibited the angiotensin-converting enzyme by 98.92%, 89.23%, 73.45%, and 65.40% at a lower concentration of 200 μg/ml. Similarly, the methanol extract at 700C of red seaweeds, *Ahnfeltiopsis flabelliformis, and Laurencia okamurae* has been reported to exhibit a strong inhibitory effect angiotensin-converting enzyme by 97.59% and 78.01% at a concentration of 200 μg/ml. Further, the methanol extract at 70 °C of red seaweeds *Grateloupia filicina, Sinkoraena lancifolia, Grateloupia elliptica, Grateloupia lanceolata,* and *Laurencia okamurae* exhibited an inhibitory effect on ACE by 83.14%, 80.86%,68.13%, 89.04%, and 69.80% at 200 μg/ml of concentration [59]. This study revealed the presence of ACE like inhibitors in red seaweeds. Protein-derived hydrolysate in *Palmaria palmate* (red seaweed) showed marked antihypertensive activity. The antihypertensive activity was exerted via inhibition of angiotensinconverting enzymes [46]. Further, an enzymatic hydrolysate of a red seaweed *Pyropia columbina* exhibited an inhibitory effect on the angiotensin-converting enzyme with an IC50 value of 1.2 mg/ml [58].
