**b.Green seaweeds**

Among the green seaweeds, few studies have been reported regarding the inhibitory effect on the angiotensin-converting enzyme. Crude and saponified extracts of *Ulva ohnoi*, *Derbesia tenuissima,* and *Oedogonium intermedium* exhibited an inhibitory effect on the angiotensin-converting enzyme. The crude extract of *Ulva ohnoi*, *Derbesia tenuissima,* and *Oedogonium intermedium* had a less potent inhibitory effect at 10 mg/ml. In contrast, the saponified extract of *Ulva ohnoi*, *Derbesia tenuissima,* and *Oedogonium intermedium* inhibited 1.9%, 1.47%, and 7.37% compared to the positive control captopri*l* (6.15% inhibition at 200 μg/ml). However, carotenoids; siphonaxanthin, neoxanthin, 9′-*cis-*neoxanthin, loroxanthin, violaxanthin, lutein, siphonein, α-carotene, and β-carotene present in green seaweeds are found to be poor inhibitors of ACE [37]. Further, a protein-derived hydrolysate of an edible green seaweed *Enteromorpha clathrata* had a potent inhibitory effect on ACE [58].
