**b.Green seaweeds**

The chloroform and ethanol fractions of green seaweed, *Capsosiphon fulvescens* showed a potent inhibitory action on the AR enzyme [50]. The authors further carried out isolation of compounds, and the isolated compounds (capsofulvesin A, B, and chalinasterol) demonstrated high inhibitory action on AR enzyme with IC50 values of 52.53, 101.92, and 345.27 *μ*M, respectively.

### **c.Red seaweeds**

Regarding red seaweeds, the bromophenol compounds present in red seaweeds have been identified as effective therapeutic agents. The bromophenols such as bis (2,3,6-tribromo-4,5 -dihydroxy phenyl) methane, 2,2′,3,6,6′-pentabromo-3′,4,4′,5-tetrahydroxydibenzyl ether, and 2,2′,3,5′,6-pentabromo- 3′,4,4′,5-tetrahydroxydiphenylmethane isolated from red seaweed, *Symphyocladia latiuscula* are well known for their inhibitory effects on aldose reductase. This enzyme is responsible for the fructose formation in the polyol pathway [25].
