**5. Conclusion**

*M. charantia* L. has been broadly studied globally for its medicinal properties and to treat a number of diseases like diabetes, dyslipidaemia, obesity, and certain cancers. The extracts of fruits and different compounds seem to exert their beneficial effects via several mechanisms like PPARs, LXRs and SREBPs mediated fat metabolism in various tissues, reduces visceral fat accumulation and adipose hypertrophy. Isolated compounds from this plant like cucurbitane type of terpenoids, flavonoids and phenolic acids possesses antiobesity potential. These mechanisms will be directly related to controlling and treating diabetes mellitus, dyslipidaemia, obesity and related cardiovascular complications. Thus, further studies are required to conduct more double blind randomized trials with bitter melon extracts in obese population. In this chapter, we summarized phytoconstituents of bitter melon and its antiobesity potential. This compilation of phytochemicals and antiobesity activity of *Momordica charantia* L. will help the researchers in designing new untried strategies.
