*1.1.5 Extracorporeal photopheresis (ECP)*

ECP is a method, in which white blood cells are separated from plasma and are being treated extracorporeally with 8-methoxypsoralen (8-MOP) followed by exposure to ultraviolet A (UVA) light. The treated cells are then returned into patient's circulation. Initially used in the treatment of T-cell lymphoma, its indications have expanded in solid organ transplantation (heart, lung, and kidney). In renal transplantation ECP was used in recurrent and refractory rejection, as well as in antibody-mediated chronic rejection with conflicting results [7].
