**6. Conclusion**

It is important to comment that current evidence regarding lipoinjection with adipose stem cells suggests that they can increase the permanence of the grafted fat to a certain degree; however, it is essential to explain to patients that this procedure can be repeated to obtain a better result in the medium and long term.

We believe that lipoinjection alone or with adipose stem cells is an excellent alternative to improve appearance in patients suffering from a wide range of craniofacial malformations or sequelae.

The search for a more youthful appearance is constant; therefore, we consider that lipoinjection as facial contouring, or in combination with other rejuvenation techniques, currently constitute an excellent therapeutic resource in facial esthetics.

Finally, we consider that the facial image plays a significant role in psychosocial development and integration. We believe that volumetric lipoinjection with or without adipose stem cells represents an excellent alternative to obtain greater facial esthetic harmony, which directly contributes to the self-esteem of children and adult patients.
