**6. Conclusions**

HSV keratitis due to its multiform occurrence remains a challenging diagnostic in clinical practice. Modern imaging technique, such as optical coherence tomography or confocal microscopy as well as modern laboratory testing including multiplex dot hybridization (MDH) assay, immunochromatographic assay (ICGA, AmpliVue) are useful in guiding the diagnostic process.

Ocular surface homeostasis should be always considered when treating HSV keratitis, especially in the neurotrophic keratitis at different severity grades.
