**Appendix**

#### **Fortified topical antibiotic formulations and mode of preparation**

Tobramycin 14 mg/mL or gentamicin 14 mg/mL


Cefazolin 50 mg/mL or ceftazidime 50 mg/mL


Amikacin 10–40 mg/mL


Vancomycin 15 mg/mL, 25 mg/mL, or 50 mg/mL


Linezolid 2 mg/mL (for methicillin-resistant Staphylococcus aureus)

1. May be used directly from parenteral linezolid intravenous infusion available as 200 mg/100 mL.

Colistin 0.19% (for multiple drug-resistant *Pseudomonas aeruginosa*)


Trimethoprim (16 mg/mL) - sulfamethoxazole (80 mg/mL)

1. Commercial intravenous preparation may be used as topical solution without preparation.

Imipenem – cilastin (1%)


*Data retrieved from [153].*
