**3. Conclusions**

The improvements of retinal sensitivity in the new area of fixation (TRL) go hand in hand with an improvement in the quality of vision and the quality of life. Before low-vision rehabilitation with audio-biofeedback, the visually impaired patient is submitted to the Italian version of the Veterans Affairs (VA) Low-Vision Visual Functioning Questionnaire (LV VFQ-48) [8] based on the idea of Stelmack JA et al. [9] and with the permission of the authors. LV VFQ-48 is a fundamental instrument for measuring the difficulty low-vision persons have in performing daily activities and evaluating vision rehabilitation outcomes.

**Figure 30.** *Stabilization of fixation.*

**Figure 31.** *Example of chessboard pattern used for audio-biofeedback.*

After rehabilitation with audio-biofeedback, there was a positive change in the score regarding better vision in activities of daily living.

The chessboard pattern has an alternating reversal presentation. This leads to a neuro-visual stimulation of retina cells and consequently to a stimulation of the visual cortex with a cerebral reorganization based on the new occipital projection of the new PRL, which replaces the nonfunctioning macula [10, 11].

In conclusion, audio-biofeedback can stabilize the PRL with increased retinal sensitivity and improvement in BCEA, represented by a decrease in the fixation area. It can also lead to the development of a new area of fixation called the trained retinal locus (TRL).

Audio-biofeedback contributes to the patient's awareness of "where to look to see better." As such, ABFB for low-vision rehabilitation can improve both the quality of vision and the quality of life.

**Figure 32.** *Example of chessboard pattern used for audio-biofeedback.*

**Figure 33.** *Stargardt disease before audio-biofeedback.*

**Figure 34.** *Microperimetry in Stargardt disease after audio-biofeedback.*

**Figure 35.** *Microperimetry in best disease after audio-biofeedback.*

**Figure 36.** *Myopic macular degeneration.*
