**1. Introduction**

Most patients with advanced ovarian cancer will suffer from recurrence, because the five year overall survival for stage FIGO III and IV epithelial ovarian cancer is still very low with 20–30%. Thus, gynecologic oncologists are looking for better treatment strategies [1].

In most patients with advanced ovarian cancer the spread to the peritoneum is the primary site of failure. Thus, it seems reasonable to assess additional local treatment strategies apart from maximal tumor debulking. According to prior studies the intraperitoneal application of cisplatin is assiciated with a 20-fold higher concentration in the intraperitoneal space compared to that measured in plasma after intravenous administration. Furthermore it was shown that the combination of postoperative intraperitoneal and intravenous (ip/iv) chemotherapy improves survival in women with optimally resected stage III ovarian cancer compared with iv chemotherapy alone. There are many aspects like treatment-related toxicities, adhesion barriers after surgery, dysfunction of implanted i.p. catheters (Tenckhoff catheters), the absence of a standard treatment regimen, patients` preference and the inconvenience of an inpatientregimen that prevent the integration of ip/Iv chemotherapy into clinical routine [2].
