**5.The 'miRNA-ome' and other non-coding RNAs**

A pathogenic role for miRNA in SCST can be indicated by the identification of aberrant miRNA processing in SLCT and gynandroblastomas. However, studies of the 'miRNA-ome' have been limited. Rosario *et al.* profiled miRNA expression and regulation in the KGN and COV434 cell lines [100]. They observed that COV434 cells preferentially expressed miR-17 family members whereas the KGN cells preferentially expressed members of the let-7 miRNA gene family [100]. There has not however, been any systematic studies in GCT or, to our knowledge, for other SCST.

Long non-coding (lnc) RNA's have also been implicated in oncogenesis [101]. Evidence indicates that lncRNA can produce short peptides from small open reading frames (smORFs) which can regulate biological processes [102]. The status of both lncRNA, and indeed, smORFs remains to be investigated in SCST.
