**Abstract**

*Melanoma*

Metastatic Melanoma. Biomedicines. 2020 Sep 3;8(9):327. doi: 10.3390/ biomedicines8090327. PMID: 32899183;

[35] Yeon M, Kim Y, Jung HS, Jeoung D. Histone Deacetylase Inhibitors to Overcome Resistance to Targeted and Immuno Therapy in Metastatic Melanoma. Front Cell Dev Biol. 2020

fcell.2020.00486. PMID: 32626712;

[36] Kelly ZR, Gorantla VC, Davar D. The Role of Neoadjuvant Therapy in Melanoma. Curr Oncol Rep. 2020 Jun 29;22(8):80. doi: 10.1007/s11912-020-

PMCID: PMC7555584

Jun 17;8:486. doi: 10.3389/

00944-5. PMID: 32601947.

PMCID: PMC7311641.

**10**

Currently, melanoma of uvea is the most well-known essential tumor, which is intaocular and malignant. Treatment using radiation has now supplanted enucleation as the therapy of decision. Radioactive eye plaques and treatment using proton are being the two most examined radiotherapeutic modalities. All the more as of late, stereotactic radiosurgery and fractionated stereotactic radiotherapy have risen as promising, non-intrusive medicines for uveal melanoma. Technique called stereotactic radiosurgery might be viewed as like "not surgery" on the grounds no extractions are included. All things being equal, it is a serious strategy for radiation treatment that conveys high dosages of radiation to exceptionally little territories and volumes.

**Keywords:** intraocular tumor, uveal melanoma, radiotherapy, stereotactic radiosurgery
