**9. Conclusion**

AM is an uncommon malignancy of the anorectal region with high malignant potential. Early diagnosis and treatment are required to achieve good long-term results. Surgical excision remains the mainstay of curative treatment. AM shows poor response to radiotherapy and conventional chemotherapy. Targeted therapies, in the recent years, have shown promising results. Future studies with the use of a combination of chemotherapy, immune check point inhibitors, BRAF inhibitors, and MEK inhibitors are required to improve the long-term survival.
