**3. Conclusions**

*S. aureus* is an important clinical pathogen for humans that has developed the ability to bind to various components of the extracellular matrix of a wide range of cells and has generated mechanisms that allow its survival and persistence in adverse conditions such as the formation of biofilms. and intracellular infection, which overwhelmingly evades the host's immune response in various human tissues.

On the other hand, it has also been possible to integrate with other important bacterial communities of the nose and skin to form part of the normal microbiome of these sites, but it can also survive in other tissues where it is not considered a normal microorganism, as is the case of the pharynx or intestines.

Although there are many studies of the colonization mechanisms and interactions of *S. aureus* in the nose, there is little information on the processes and interactions that it performs in the pharynx. Therefore, additional studies of the pharynx as a site of colonization of *S. aureus* are required.
