**6. Conclusion**

The primary type of hypopharyngeal cancer is squamous cell carcinoma, with a poor prognosis. Approximately up to a third of patients are diagnosed with second primary esophageal cancer. The infrequent incidence of hypopharyngeal cancer limits the extensive clinical trial application. Early-stage disease achieved successful tumor management after treatment (radiation alone or surgery resection). However, despite the improvements of therapy, measures alone may not be sufficient to preserve the laryngeal function in advanced-stage ones. Formulating an accurate and useful treatment plan depends on a comprehensive assessment of the patient's general condition and tumor staging before treatment. To explore a functional tumor remission and improve survival outcomes, researchers are seeking a balance between swallowing-voice rehabilitation and organ preservation. Also, the treatment requires cooperation involved specialized expertise and a multi-disciplinary team to benefit patients. Future directions will focus on refining surgery to afford functional organ preservation and radiotherapy techniques. Furthermore, it is important to regard to influence patient outcomes; there also needs to be more emphasis on non-surgery therapy's toxicity.
