Meet the editor

Dr. Polona Žigon is a senior scientist at the Department of Rheumatology, University Medical Center Ljubljana, Slovenia, and is a teaching assistant at the Faculty of Mathematics, Natural Sciences, and Information Technologies, University of Primorska, Slovenia. She obtained an MSc in Clinical Biochemistry in 2008 and a Ph.D. in Biomedicine in 2014 at the Faculty of Pharmacy, University of Ljubljana. During her post-graduate studies, she

completed a six-month research internship in the School of Medicine, Hokkaido University Sapporo, Japan. She is a member of the Slovene Chamber Laboratory Medicine, a working member of EMEUNET, and a member of the Autoimmunity Network. Her research in the field of systemic autoimmune diseases resulted in more than thirty original scientific articles published in peer-reviewed journals, six book chapters, and one patent application.

Contents

**Section 1**

*by Polona Žigon*

**Section 2**

**Section 3**

**Preface III**

Introduction **1**

**Chapter 1 3**

Clinical Aspects of the Antiphospholipid Syndrome **17**

**Chapter 2 19**

**Chapter 3 49**

**Chapter 4 71**

of Antiphospholipid Syndrome **91**

**Chapter 5 93**

**Chapter 6 103**

Introductory Chapter: Antiphospholipid Antibodies - A Laboratory Criterion for the Antiphospholipid Syndrome, but Also Bystanders

*by Kathryn Grimes, Adam P. Klein, Rakhee Lalla, Adeolu Morawo,* 

*Sana Somani, Matthew J. Woodward and John W. Cole*

Bleeding in Patients with Antiphospholipid Antibodies

Trends and Novelties in the Diagnosis and Pathogenesis

A Novel Autoantibody against β2-Glycoprotein I/HLA Class II

Extracellular Vesicles: Intercellular Communication Mediators

*by Ula Štok, Saša Čučnik, Snežna Sodin-Šemrl and Polona Žigon*

*by Kenji Tanimura, Yuki Sasagawa, Masashi Deguchi, Noriko Arase,* 

in Infections, Cancer, and Other Conditions

Antiphospholipid Syndrome and Stroke

Obstetric Antiphospholipid Syndrome *by Ariela Hoxha and Paolo Simioni*

*by Peter Kubisz, Pavol Holly and Jan Stasko*

Complexes in Antiphospholipid Syndrome

*Hisashi Arase and Hideto Yamada*

in Antiphospholipid Syndrome
