*3.2.4 Conclusions/future directions*

DeltaRex-G is a potent cytotoxic cell cycle checkpoint inhibitor. Complete and partial responses were observed at dose levels II and III, suggesting a significant dose–response relationship between the dose of DeltaRex-G given and the level of response seen in the tumors. This relationship is further implied by the increase in months of progression free survival as the dosages were increased. Additionally, CCNG1 is expressed in over 50% of various different malignancies other than pancreatic cancer, suggesting DeltaRex-G's potential efficacy in other cancer types [10].
