**Acronyms and abbreviations**


**43**

**Author details**

Doha, Qatar

Mohammed Ussama Al Homsi2

Corporation, Doha, Qatar

*Evolving Dynamic Biomarkers for Prediction of Immune Responses to Checkpoint Inhibitors…*

sCTLA-4 soluble cytotoxic T-lymphocyte-associated protein 4 sTIM-3 soluble T-cell immunoglobulin and mucin domain-3

MICA major histocompatibility complex class I-related chain A MICB major histocompatibility complex class I-related chain B

sICs soluble forms of immune checkpoints ICI immune checkpoint inhibitors

sPD-1 soluble programmed cell death protein 1 sPDL-1 soluble programmed death-ligand 1 sPDL-2 soluble programmed cell death 1 ligand 2

sLAG-3 soluble lymphocyte-activation gene 3 sIDO soluble indoleamine 2,3-dioxygenase sCD163 soluble cluster of differentiation 163

sNKG2DL soluble natural killer group 2D ligands

ULBP 1,2,3,4 UL-16-binding proteins 1,2,3,4 RAET1G retinoic acid early transcript 1G RAET1L retinoic acid early transcript 1 L sCD27 soluble cluster of differentiation 27 sCD28 soluble cluster of differentiation 28

Afsheen Raza1,2†, Maysaloun Merhi1,2†, Allan Relecom3†, Queenie Fernandes1,5†,

2 National Center for Cancer Care and Research, Hamad Medical Corporation,

3 Department of Oncology, Geneva University Hospitals, Geneva, Switzerland

4 Translational Research Institute, Academic Health System, Hamad Medical

© 2021 The Author(s). Licensee IntechOpen. This chapter is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/ by/3.0), which permits unrestricted use, distribution, and reproduction in any medium,

1 Translational Cancer Research Facility and Clinical Trial Unit, Interim Translational Research Institute, Hamad Medical Corporation, Doha, Qatar

and Said Dermime1,2\*

, Shahab Uddin4

,

Varghese Inchakalody1,2†, Abdul Rahman Zar Gul2

5 College of Medicine, Qatar University, Doha, Qatar

\*Address all correspondence to: sdermime@hamad.qa

provided the original work is properly cited.

† These authors equally contributed in writing this book chapter.

*DOI: http://dx.doi.org/10.5772/intechopen.96494*

ORR overall response rate

NKG2D natural killer group 2D

NK natural killer NKT natural killer T cells *Evolving Dynamic Biomarkers for Prediction of Immune Responses to Checkpoint Inhibitors… DOI: http://dx.doi.org/10.5772/intechopen.96494*

