*3.2.2 Methods*

Twenty patients with chemotherapy-resistant metastatic pancreatic cancer were enrolled in the trial. Target lesions were identified in each patient and changes in tumor size were measured using RECIST v1.0 criteria. Patients were grouped and treated at 3 escalating doses of DeltaRex-G, with six patients at Dose 0-I, seven patients at dose level II, and seven patients at dose level III. Fifteen patients completed at least one full 4-week treatment cycle and had a follow-up PET-CT scan. These fifteen subjects comprised the modified intent-to-treat (mITT) population and were evaluated in terms of their response to the treatment, months of progression-free survival and months of overall survival.
