**4. Conclusions**

Peptic ulcer complications are still remarkable medical problem. Although the current medical therapy of peptic ulcer, as PPI drugs, control of *H. pylori* infection, the decrease of the disease frequency was not followed by reduction of complications. Bleeding, perforation, and gastric-pyloric obstruction are evident. Proper treatment for bleeding encloses urgent medical approach and frequently therapeutic endoscopic procedures, usually followed by favorable evolution of complication. The failure of these therapies requires the surgery. For the perforation the central therapeutic role is usually played by surgical procedures; the opportunities for conservative therapy are limited. Gastric-pyloric obstruction can be treated with endoscopic approach and balloon dilation; in case of failure, the surgery is necessary.
