**17.3 IL-5 inhibitor**

AntiIL5 antibody has been studied in both pediatric and adult patients with EoE. Mepolizumab significantly reduced esophageal eosinophilia but there was minimum symptomatic improvement [52]. Reslizumab also improved esophageal eosinophilia in EoE but there was no difference in clinical improvement in comparison to placebo [53, 54].
