**4. Sedation indications**

In most countries, procedural sedation and analgesia (PSA) is common practice in order to promote the success and ease of different diagnostic and therapeutic procedures which do not need muscle paralysis.

Alongside gastroenterology, many other medical disciplines, such as cardiology, gynecology, dentistry, radiology, dermatology, plastic surgery, and emergency medicine, are currently using PSA, and the list is ever expanding. The primary clinician and the patient make a mutual decision to carry out the procedure under PSA.
