**7. Conclusion**

This review has examined the association of kisspeptin with female infertility and concluded that kisspeptin has a key role in the HPG axis and can be potentially used for the treatment of reproductive disorders including hypogonadism, ovarian hyperstimulation syndrome (OHSS), polycystic ovary syndrome (PCOS), unexplained infertility (UI), male factor infertility (MFI), hypothalamic amenorrhea (HA), and endometriosis. The literature review revealed that no adverse effects were reported after kisspeptin administration in healthy individuals and patients. Therefore, kisspeptin can be used safely in both healthy and infertile individuals. Especially its positive effects on GnRH and its key role in the initiation of physiological events in the hypothalamic–pituitary-gonadal axis (HPG axis) show that kisspeptin has a say in fertility. For this reason, kisspeptin is an option that should be focused on in the solution of infertility cases that develop in mammals (humans and especially livestock) and are one of the diseases of the age.

*Kisspeptin: Role in Female Infertility DOI: http://dx.doi.org/10.5772/intechopen.94925*
