**5.7 B cell in Graves' Disease**

Monoclonal antibody to the CD 34 antigen on the surface of B cells has demonstrated that changing the B cell repertoire can have profound influences on

Graves' Disease [40]. B cell also plays an important role in TSHR-Ab interaction with retro-orbital TSHRs which expressed on fibroblasts and adipocytes cause Graves Ophthalmology [95].
