**5.8 T cell in Graves' Disease**

T cells are present in the immune repertoire react with appropriate peptides which are derived from thyroid autoantigens in Graves' Disease. Secretion of thyroid-specific autoantibodies from B cells is increase against the activated T cells. The thyroid-specific T cells in Graves' Disease primarily act as helper (CD4+ Th1) cells. However, based on the production of cytokines, subsets of T cells have been distinguished most easily

