**5.3 TSH receptor and autoantibodies**

Long-acting thyroid stimulator (LATS) was found among patients with Graves' hyperthyroidism [86] and it is proved to be an immunoglobulin which inhibited the binding of radiolabeled thyroid stimulating hormone to thyroid membranes due to the presence of antibodies to the TSH receptor (TSHR-Ab) [87].
