**6. Conclusions**

We have clinically characterized a large population of patients with skin NSAIDinduced reactions by means of controlled oral challenges, and we have proposed a working classification of these clinical entities, which can be recognized through the distinct clinical features and the challenge results. Skin NSAID hypersensitivity have showed at least 5 well-defined clinical phenotypes. This classification based on clinical phenotypes is a real and practical approach in the daily clinic, which will allow us to make the best-appropriated diagnostic and therapeutic decisions.

### **Conflict of interest**

The authors declare no conflict of interest.

*Clinical Phenotypes in NSAID-Induced Urticaria/Angioedema DOI: http://dx.doi.org/10.5772/intechopen.96718*
