**Table 1.**

*Skin clinical phenotypes of NSAID hypersensitivity.*

Since CSU is often a self-limiting disease within months to years, NECD can potentially remit with the resolution of CSU. However, NECD patients seem to have a distinct phenotype compared with NSAID-tolerant CSU patients: the latter have a shorter duration of CSU and less often have angioedema when compared with NECD patients [9].
