b.LUX-VALVE

LUX-Valve (Jenscare Biotechnology, Ningbo, China) is a self-expanding valve that is inserted through the right atrium via a minithoracotomy and anchored throught a dedicated mechanism to the leaflets and the interventricular septum. Lu et al. published their first-in-human experience in 12 patients with severe TR and functional class IV [55]. The procedure was successful in all patients, but one patient required surgery due to bleeding and another died of an acute myocardial infarction. A decrease in TR was observed in all cases, with only one of them with a residual moderate leak. The largest series to date with results from 35 patients with severe TR and functional class III/IV has recently been communicated [56]. The mortality rate at 30 days was 5.7%, with significant clinical improvement in NYHA functional class and a decrease in right ventricle volume.
