*3.2.2 Synthetic polymers*


6.Magneto-responsive polymeric systems are comprised of polymer networks that are physically or chemically functionalized with magnetic nanoparticles (of magnetic elements such as iron, cobalt, nickel or their oxides). When these particles are covalently immobilized or physically entrapped (by blending, in situ precipitation or dip coating), they respond to magnetic field. This property enables spatio-temporal control over the physical, structural and mechanical properties of the polymeric scaffold. Leaching out of magnetic nanoparticles (< 50 nm) from these materials and their ability to cross the biological membrane, thus inducing inflammation, generating ROS, impeding DNA function and driving cell apoptosis limits them incorporation in the polymeric networks [42].
