**Acknowledgements**

The authors are grateful to the RC Biotechnology and InaCC-RC Biology-Indonesian Institute of Sciences (LIPI) for their valuable support to complete this study. We express our gratitude to Dra. Herdini, M.Si., Apt. and Ika M. Kusuma SP. M.Si., Lecturer at Fac. of Pharmacy-ISTN, Jakarta for suggestions during the research. We are also much thankful to the Faculty of Veterinary Medicine- IPB University, for providing us facilities and collaboration.
