**9.3 Pyronaridine**

Pyronaridine was developed in 1970 at the Institute of Chinese Parasitic Disease [83, 84], and has been used in clinical trials in China since the 1980s. It is one of the components of the artemisinin combination therapy pyronaridine/artesunate and has been shown to be effective against chloroquine-resistant strains (Pyramax). It's also being investigated as a possible anticancer medication and Ebola treatment. Pyonaridine, like lumefantrine, tends to interfere with haematin, but it does not seem to share resistance mechanisms with chloroquine [85]. Pyronaridine is a form of pyronaridine that is The most common side effects of pyronaridine are headache, vomiting, stomach pain, bradycardia, and hypoglycemia.
