Meet the editor

Professor Dr. Shailendra K. Saxena is a vice dean and professor at King George's Medical University, Lucknow, India. His research interests involve understanding the molecular mechanisms of host defense during human viral infections and developing new predictive, preventive, and therapeutic strategies for them using Japanese encephalitis virus (JEV), HIV, and emerging viruses as a model via stem cell and cell culture technologies. His research

work has been published in various high-impact factor journals (*Science, PNAS, Nature Medicine*) with a high number of citations. He has received many awards and honors in India and abroad including various Young Scientist Awards, BBSRC India Partnering Award, and Dr. JC Bose National Award of Department of Biotechnology, Min. of Science and Technology, Govt. of India. Dr. Saxena is a fellow of various prestigious international societies/academies including the Royal College of Pathologists, United Kingdom; Royal Society of Medicine, London; Royal Society of Biology, United Kingdom; Royal Society of Chemistry, London; and Academy of Translational Medicine Professionals, Austria. He was named a Global Leader in Science by *The Scientist*. He is also an international opinion leader/expert in vaccination for Japanese encephalitis by IPIC (UK).

Contents

**Section 1**

**Section 2**

**Section 3**

for Precision Medicine

Diseases: Options and Challenges

for Drug Target and Biologic Drug Discovery *by Shengya Cao and Nadia Martinez-Martin*

*by Fawzi Faisal Bokhari and Ashwag Albukhari*

*and Shailendra K. Saxena*

for Drug Discoveries

**Section 4**

**Preface XIII**

for Precision Medicine **1**

**Chapter 1 3**

High-Throughput Screening Based Drug Discovery for Infectious Diseases **13**

**Chapter 2 15**

High-Throughput Screening for Novel Drug Designing/Development **27**

**Chapter 3 29**

**Chapter 4 53**

for Novel Drug Designing/Development **71**

**Chapter 5 73**

*by Shailendra K. Saxena, Vimal K. Maurya, Saniya Ansari, Swatantra Kumar,* 

Introduction: High-Throughput Screening Based Drug Discovery

Introductory Chapter: High-Throughput Screening - A New Tool

High-Throughput Screening for Drug Discovery toward Infectious

Unbiased Identification of Extracellular Protein–Protein Interactions

Design and Implementation of High Throughput Screening Assays

High-Throughput Screening Based Cell Signalling Modulators

Targeting the Aryl Hydrocarbon Receptor (AhR): A Review of the In-Silico Screening Approaches to Identify AhR Modulators *by Farag E.S. Mosa, Ayman O.S. El-Kadi and Khaled Barakat*

*by Ankur Gupta, Swatantra Kumar, Vimal K. Maurya, Bipin Puri* 

*Shivani Maurya, Ankur Gupta, Anil K. Tripathi and Bipin Puri*
