**4. Depression and cognition**

In relation with the cognitive status, generally 40–70% of MS patients will present impairments in correlation with the disease type. Studies in the literature have concluded that clinically significant depression could conduce to a even more visible impairment in a patient's cognitive capacities. Studies by Arnett et al. [12–14], revealed that depression can affect in a negative way the working memory, especially the executive component. The conclusions exposed before suggest the probability that compensating the emotional disorders as depression have the possibility of influencing in a beneficial way the cognitive capacity in a multiple sclerosis patient, this theory was not demonstrated yet.
