**3. Epidemiology of peripheral neuropathy in ANCA-associated vasculitis**

Peripheral neuropathy is common in ANCA-associated vasculitis and can be the first manifestation of the disease. The prevalence of PN is variable depending on the type of AAV. It is particularly higher in EGPA (60–80%) than in MPA (40–50%) and GPA (20–25%) [8–14]. Vasculitis-related neuropathies are also seen in other systemic diseases such as cryoglobulinemic vasculitis associated with chronic hepatitis C virus (HCV) with a prevalence of 60% and in primary Sjogren syndrome [14] and rarely in large-vessel vasculitis [14] and other connective tissue diseases such as systemic lupus [15].
