**5. Conclusion**

There is no one specific model showing all the factors involved in the pathogenesis of multiple sclerosis, so the researchers attempt to acquire a spacious range of examples that can imitate various MS features. Extremely, the development of alternative and mixed models will contribute to an improved understanding of multiple sclerosis and its treatment. With the help of animal models, information on response to treatment can be extrapolated. The development of models better able to reproduce the pathological changes of MS constitutes the beginning stage in the development of novel treatments; however, we are most likely to achieve a genuine understanding of MS through data from patients. The existing examples have shown useful in the evolution of MS treatment, and further integration of these examples will help further our understanding of the etiology.
