**6. Conclusions**

In this chapter, the lytic bacteriophages' efficacy has been reported. Therapeutic bacteriophages have been shown to prevent the growth and replication of a variety of pathogenic bacteria in humans, resulting in improved recovery, health, and survival of infected individuals. Since no or few side effects have been reported, phage therapy is medically safe and effective against bacterial infections. Personalized treatment is presented for phage-resistant gangrene bacterial strains, burn wounds, chronic ulcers, psoriasis, bacterial diarrhoea, urinary tract infections, pneumonia and tuberculosis. Producing higher-quality phage cocktails against specific bacteria groups and making them readily available in all areas, regardless of geography, economics, or climatic conditions, is, however, advantageous. Phage therapy is one of the most effective methods for controlling microbial infections that occur in a variety of species at different times. Expanding research to other organisms may be one of the most useful techniques for collecting evidence and validating the phage therapy's utility and therapeutic potential. Understanding infection mechanisms, phage tolerance, phage therapy effectiveness on targeted pathogens, and their effects on the normal microbiome can all aid in improving biocontrol strategies. A scientific logical approach is needed to develop long term storage and transport of therapeutic bacteriophages with a common guideline for the use and safety of phage therapy. The production of new medicines, innovative methods, and management practises to mitigate the risk of infectious agents being introduced and to reduce predisposing factors may be needed in the future to control bacterial diseases. The discovery of novel phage-host interaction methods and the understanding of how bacteriophages control their hosts will be aided by future studies on the complexities of phage lifestyles and dynamics, bionomics in natural systems, genome and viriome analysis, proteome analysis, genes coding for their proteins, and DNA polymerase phylogeny. To reduce the risk of infectious agents being introduced and to reduce predisposing factors, future bacterial disease control would depend on the development of new drugs, methods, and management practises. In response to the threat posed by multiresistant "super bugs," the use of phage endolysins, as well as possible applications of these enzymes in medicine, food protection, agriculture and veterinary medicine, biotechnology, and environmental sciences, has increased significantly. The significance and trend of research on bacteriophages and their applications is expected to continue as the quest for new antimicrobials intensifies in the near future.
