**5.4 Psoriasis**

Psoriasis is a common chronic skin disease causing red and itchy scaly patches on the scalp, knees, elbows, and trunk. The "Phagoburn project" aims to reduce bacterial growth and reduce the incidence of psoriasis in patients with severe inflammation and infection. "Phagobon" has been used in the treatment of phage cures to treat *E. coli* and *Pseudomonas aeruginosa* diseases. Phase I/II clinical trials were established in France, Belgium, and Switzerland. Although this project is a breakthrough in phage medical studies, *in vitro* trials and clinics are still needed to gain widespread acceptance in the use of the therapeutic phage to treat people with pathogenic diseases or MDR. A biodegradable polymer wound dressing called, "PhagoBioDerm" is impregnated with numerous antimicrobial elements containing the phage cocktail Pyophage, and the dressing exhibited a slow degradation and presentation of the antimicrobial, and the release of phage particles for a long time had been demonstrated, exhibiting higher healing of infected venous leg ulcers [36– 38, 96, 110]. The use of the PhagoBioDerm is promising for each remedy and prevention of microbial infections in wounds [36, 111]. Therapeutic bacteriophages, method of isolation, purification, and storage, units of phage, outcome of the bacteriophage therapy and reference are listed in **Table 1**.
