Preface

The application of microorganisms to produce novel bioproducts, as well as bioproducts with economic importance already established, has great value for the economy and the environment in achieving sustainable production worldwide. The *Saccharomyces* genus has considerable importance in the production of several biomolecules by fermentation with vast applications in industries such as agriculture and pharmaceuticals. Additionally, *S. cerevisiae* is a model system for studies of anticancer agents and has great relevance in medical research, being crucial to understanding tumor cells mechanisms.

This book, *Saccharomyces*, provides a comprehensive overview of the current state of the art of the use of the *Saccharomyces* genus in important areas such as agriculture and pharmaceuticals. This book reflects the value of this microorganism in related areas. It includes seven chapters in two sections: "Agricultural and Biotechnological Applications" and "Medical and Pharmaceutical Applications." Chapters in the first section discuss metabolic engineering of *S. cerevisiae* using CRIPR-Cas9 technology for producing biopharmaceuticals, fruit juice fermentation for antioxidant activity, and the mode of action of indigenous *S. cerevisiae*. Chapters in the second section discuss the performance of *Saccharomyces* as an antiviral experimental microorganism on pandemic diseases, application of yeast to study DNA repair and damage tolerance on cell cycle division, how calorie restriction can support the anti-aging process using yeast budding cells, and secondary metabolites from *S. cerevisiae* with anticancer activity.

I hope this book will be interesting for researchers around the world interested in the *Saccharomyces* genus. I also hope these microorganisms can be applied to diverse bioprocesses to produce novel bioproducts useful for new discoveries.

> **Thalita Peixoto Basso and Luiz Carlos Basso** University of São Paulo, Brazil

**1**

Section 1

Agricultural and

Biotechnological Applications

Section 1
