Meet the editors

Thalita Peixoto Basso received her bachelor's degree in Agriculture Engineering. During this period, she studied the fermentation characteristics of *Saccharomyces cerevisiae* isolated from ethanol industrial processes. She obtained her master's degree from the University of Sao Paulo (ESALQ/USP). During this time, she isolated and selected fungi with high cellulose activity for enzymatic hydrolysis of sugarcane bagasse. Dr. Basso

received her Ph.D. in the Agricultural Microbiology Program at ESALQ/USP, with a period as a visiting scholar at the University of California Berkeley and Energy Bioscience Institute. Meanwhile, she worked on the improvement of *S. cerevisiae* by hybridization for increased tolerance toward inhibitors from second-generation ethanol substrates. Currently, she is a collaborating professor and a postdoc working with metabolomics and proteomics of fermentation processes at the Genetics Department of ESALQ/USP.

Luiz Carlos Basso obtained a bachelor's degree in Agriculture Engineering and a master's degree in Soil and Plant Nutrition from the University of Sao Paulo (ESALQ/USP), in 1969 and 1973, respectively. He obtained a Ph.D. in Biological Science from São Paulo State University (UNESP), Brazil, and postdoctoral degrees from Institut des Produits de la Vigne, Montpellier (1989), and Superior Technical Institute, Lisbon. Since 1980,

Dr. Basso has been involved with yeast biochemistry and physiology, aiming to increase ethanol yield using the fed-batch industrial process. During the last fifteen years, he has conducted a yeast selection program resulting in the most widely used *Saccharomyces cerevisiae* strains (PE-2 and CAT-1) in the Brazilian ethanol industry. Currently, Dr. Basso is a senior professor at ESALQ/USP teaching Biochemistry (for undergraduate students) and Biochemistry and Physiology of Yeast Fermentation (for graduate students) and selecting tolerant strains for lignocellulosic inhibitors.

Contents

**Section 1**

Biotechnology

**Section 2**

*by Michael Fasullo*

*cerevisiae* CCMB 520

*by Seyma Hande Tekarslan-Sahin*

and Performance in Animals *by Shakira Ghazanfar*

*by Nilay Seyidoglu and Cenk Aydin*

*Eka Triwahyuni and Muryanto*

Checkpoint Control of DNA Repair in Yeast

*Tonny Leite, Sandra Assis and Amanda Sena*

**Preface III**

Agricultural and Biotechnological Applications **1**

**Chapter 1 3**

**Chapter 2 17**

**Chapter 3 37**

Medical and Pharmaceutical Applications **57**

**Chapter 4 59**

**Chapter 5 71**

**Chapter 6 97**

Metabolic Engineering of *Saccharomyces cerevisiae* for Industrial

Biotransformation of Pitanga Juice by Tannase from *Saccharomyces* 

*by Gustavo Monteiro, Maria Araújo, Paula Barbosa, Marcelo Mello,* 

Understanding the Mechanism of Action of Indigenous Target Probiotic Yeast: Linking the Manipulation of Gut Microbiota

Saccharomyces: Is a Necessary Organism or a Biological Warrior?

The Budding Yeast *Saccharomyces cerevisiae* as a Valuable Model

*by Yanni Sudiyani, Muhammad Eka Prastya, Roni Maryana,* 

Organism for Investigating Anti-Aging Compounds
