**4. Conclusion**

Thus, acute and chronic cerebrovascular disorders in patients with CKD of the pre-dialysis and dialysis periods are the most frequent and formidable complications that develop against the background of "traditional" and "specific" cerebrovascular risk factors. Because of the studies, new knowledge was obtained about the species diversity and species representation of the microbiocenosis of the colon lumen in patients with chronic kidney disease receiving program dialysis. The inclusion of the author's immobilized multistrain synbiotic "LB-complex L" as a dietary component in the basic therapy allows not only to restore the evolutionarily determined microbiocenosis, but also improves the quality of life of patients, and also helps to reduce the risk of cardiovascular events.

Active control of the described specific indicators (impaired phosphoruscalcium metabolism and calcification of the arterial bed, correction of anemia and dysfunction of blood corpuscles, hyperhomocysteinemia and hyperβ2 microglobulinemia, accumulation of uremic toxins and toxins of intestinal bacteria, correction of pathologically altered intestinal microbiocenosis) and conditions of dialysis their timely prevention, as well as the correction of intradialysis hypo-/ hypertension, are necessary for the timely prevention of cerebrovascular disorders in dialysis patients.
