**1. Introduction**

The prevalence of chronic kidney disease (CKD) is comparable to such socially significant diseases as hypertension, coronary artery disease, diabetes mellitus, obesity, metabolic syndrome throughout the world. The incidence is according to various sources 10–20% [1, 2]. The number of patients with CKD is progressively increasing and reaching the nature of a pandemic according to the opinion of some scientists [3, 4]. As a result, the number of patients receiving renal replacement therapy is growing (currently, more than 2 million people all over the world). In this connection, the share of the annual increase of dialysis programs is estimated at 6–12% [5].
