Preface

**Chapter 7 125**

**Chapter 8 143**

**Chapter 9 157**

Effects of Physiotherapy Interventions on the Function of the Locomotor System in Elder Age: View of Theory and Practice

Total Antioxidant from Herbal Medicine as a Possible Tool for

Management of Sarcopenic Obesity for Older Adults with

the Multifunctional Prevention of Muscular Atrophy

*by Tsan-Hon Liou, Chun-De Liao and Shih-Wei Huang*

*by Boglárka Debity and Julianna Cseri*

Lower-Extremity Osteoarthritis

*by Viani Anggi*

**II**

The loss of skeletal muscle mass and strength substantially impairs physical performance and the quality of life, especially in older patients. The prevention and treatment of muscle atrophy is a big challenge for clinicians and other professionals. The book chapters provide insight into the molecular, morphological, and functional changes under conditions that lead to muscular atrophy. The sarcopenia in older patients is highlighted in many chapters. The normal situation and the age-related changes in the motor unit (motor neuron, neuromuscular junction, and skeletal muscle) are demonstrated and the role of impaired bone remodeling are presented in some chapters. Other chapters present and discuss the tools for the management of muscular atrophy (sarcopenia) in older patients and other types of muscular atrophy. The pharmacological, nutritional, and physiotherapeutic approaches are demonstrated in detail, as well as the possible role of herbal antioxidants in the treatment of muscular atrophy. The chapters may be interesting for professionals in clinical practice, for medical and health care students as well as for researchers working in muscle-related fields of science.

Special thanks to Romina Rovan, Author Service Manager, for professional guidance during the whole editing process.

> **Julianna, Cseri** Department of Physiotherapy, University of Debrecen, Debrecen, Hungary

**1**

Section 1

Molecular Mechanisms

of Muscular Atrophy and

Age-related Changes in

Skeletal Muscle Structure

and Function
