Meet the editor

Dr. Ane C.F. Nunes is a geneticist with a master's degree and Ph.D. in Medical Sciences and Nephrology from UFRGS/Brazil. She has postdoctoral experience in renal physiology (UFRJ/ Brazil), clinical medicine and nephrology (USP/Brazil), and nephrology and hypertension (UCI/USA). She is a Professor of Medical Genetics, Human Genetics, and Molecular Biology. Her research fields are human genetics diseases, cellular and molec-

ular biology applied to nephrology, biochemistry, and microbiology with projects in the following subjects: inflammatory markers, molecular diagnosis, DNA polymorphisms, chronic kidney disease (CKD), polycystic kidney disease (PKD), Fabry disease, rare diseases, cellular and murine models for CKD, RNA processing, fluorescent image analysis, nanoparticles development, and nanomedicine.

Contents

**Section 1**

**Section 2**

in Intensive Care

Proximal Tubule

in Hypertension

in Priority Infectious Agents

*and Ashok Palaniappan*

**Preface XI**

Pharmacology and Drugs Biomarkers **1**

**Chapter 1 3**

**Chapter 2 25**

**Chapter 3 45**

Nephrology and Renal Physiology **61**

**Chapter 4 63**

**Chapter 5 75**

**Chapter 6 109**

Computational Studies of Drug Repurposing Targeting P-Glycoprotein-Mediated Multidrug Resistance Phenotypes

P-Glycoprotein Efflux Transporters and Its Resistance

Serum Creatinine, Muscle Mass, and Nutritional Status

*by Gianlorenzo Golino, Vinicio Danzi and Silvia De Rosa*

*by Jiang Liu, Yanling Yan and Joseph I. Shapiro*

*and Valeria Aparecida Costa-Hong*

The Na/K-ATPase Signaling Regulates Natriuresis in Renal

The Effect of Dietary Sodium Restriction on Vascular Stiffness

*António Gerson Bastos Francisco, Isaura da Conceição Almeida Lopes* 

*by Henrique Cotchi Simbo Muela, Mujimbi José Viana,* 

*by Arvindh Kumar, Sangeetha Muthamilselvan*

*by Chenmala Karthika and Raman Sureshkumar*

Its Inhibitors and Therapeutic Aspects

Urological Effects of Ketamine Abuse *by John Shung-Lai Leung and Wai-Kit Ma*
