**6. Conclusion**

The homology modeling was performed to determine the best template, from which we concluded that 4m1m is preferred in *Aspergillus fumigatus, Aspergillus nidulans, Acinetobacter baumannii*, and *Candida albicans*. In *Cryptococcus neoformans* 4f4c is preferred, and 3wme is preferred in *Staphylococcus aureus*.

The molecular docking led us to conclude that bithionol, levofloxacin, e1210, tigecycline, and bithionol were the most efficient potential antibiotics for the organisms *Aspergillus fumigatus, Acinetobacter baumannii, Candida Albicans, Staphylococcus aureus*, and *Cryptococcus neoformans*, respectively. Each of the potential antibiotics was found to be more effective than a number of the known antibiotics in the treatment of that respective organism.

An analysis of the interacting residues showed us that:

