**2. Prioritizing pathogenic agents**

Opportunistic pathogens with a response profile of drug resistance to antibiotic treatment are good candidates for study. The organisms chosen here included bacteria and fungi identified by the WHO as priority pathogens [10] as well as other nosocomial pathogens that pose an elevated threat level due to acquisition of MDR over the recent years. Nosocomial pathogens are subject to the evolutionary pressure exerted by constant exposure to antibiotics in hospitals that could accelerate the emergence of pathogenicity-related mutations.
