*Microwave Heating - Electromagnetic Fields Causing Thermal and Non-Thermal Effects*

DoE, response surface methodology, and other statistical approaches are of great help to quickly determine the best conditions to achieve the highest yield of the metabolite of interest from the natural source. However, in the past year, the application of MASE in scalable industrial processes has always encountered several limitation due to the presence of some technological barriers, mainly related to the design of safe instrumentation. Thanks to the technological progress witnessed in recent years, the first industrial-scale ovens finally became commercially available [73, 74].

Food, pharmaceutical, and nutraceutical industries would be benefited from this emerging technology of MASE, which is an excellent substitute for traditional methods such as SE, and other environmentally benign technologies. The promise to be the technique that can respond to the necessities in this field will make MASE the extraction method of choice for the next years.
