**Acknowledgements**

The authors acknowledge Fundação de Amparo à Pesquisa no Estado de São Paulo, FAPESP (grant #2017/15144-9, grant #2018/26005-2), FAPESP/ CDMF (grant #2013/07296-2), FAPESP/SHELL (#2017/11986-5), FAPESP/GSK (#2014/50249-8); and FAPESP (grant #2019/26860-2).
